Flores H - Search Results

1

Heteroaromatic and aniline derivatives of piperidines as potent ligands for vesicular acetylcholine transporter.

Li J, Zhang X, Zhang Z, Padakanti PK, Jin H, Cui J, Li A, Zeng D, Rath NP, Flores H, Perlmutter JS, Parsons SM, Tu Z. Li J, et al. Among authors: flores h. J Med Chem. 2013 Aug 8;56(15):6216-33. doi: 10.1021/jm400664x. Epub 2013 Jul 18. J Med Chem. 2013. PMID: 23802889 Free PMC article.

2

Preclinical evaluation of a promising C-11 labeled PET tracer for imaging phosphodiesterase 10A in the brain of living subject.

Liu H, Jin H, Yue X, Zhang X, Yang H, Li J, Flores H, Su Y, Perlmutter JS, Tu Z. Liu H, et al. Among authors: flores h. Neuroimage. 2015 Nov 1;121:253-62. doi: 10.1016/j.neuroimage.2015.07.049. Epub 2015 Jul 26. Neuroimage. 2015. PMID: 26216275 Free PMC article.

3

Synthesis of Fluorine-Containing Phosphodiesterase 10A (PDE10A) Inhibitors and the In Vivo Evaluation of F-18 Labeled PDE10A PET Tracers in Rodent and Nonhuman Primate.

Li J, Zhang X, Jin H, Fan J, Flores H, Perlmutter JS, Tu Z. Li J, et al. Among authors: flores h. J Med Chem. 2015 Nov 12;58(21):8584-600. doi: 10.1021/acs.jmedchem.5b01205. Epub 2015 Oct 15. J Med Chem. 2015. PMID: 26430878 Free PMC article.

4

Kinetics modeling and occupancy studies of a novel C-11 PET tracer for VAChT in nonhuman primates.

Jin H, Zhang X, Yue X, Liu H, Li J, Yang H, Flores H, Su Y, Parsons SM, Perlmutter JS, Tu Z. Jin H, et al. Among authors: flores h. Nucl Med Biol. 2016 Feb;43(2):131-9. doi: 10.1016/j.nucmedbio.2015.11.003. Epub 2015 Nov 7. Nucl Med Biol. 2016. PMID: 26872437 Free PMC article.

5

Kinetic modeling of [¹⁸ F]VAT, a novel radioligand for positron emission tomography imaging vesicular acetylcholine transporter in non-human primate brain.

Jin H, Yue X, Liu H, Han J, Flores H, Su Y, Parsons SM, Perlmutter JS, Tu Z. Jin H, et al. Among authors: flores h. J Neurochem. 2018 Mar;144(6):791-804. doi: 10.1111/jnc.14291. Epub 2018 Mar 25. J Neurochem. 2018. PMID: 29315563 Free PMC article.

6

Radiosyntheses and in vivo evaluation of carbon-11 PET tracers for PDE10A in the brain of rodent and nonhuman primate.

Fan J, Zhang X, Li J, Jin H, Padakanti PK, Jones LA, Flores HP, Su Y, Perlmutter JS, Tu Z. Fan J, et al. Among authors: flores hp. Bioorg Med Chem. 2014 May 1;22(9):2648-54. doi: 10.1016/j.bmc.2014.03.028. Epub 2014 Mar 26. Bioorg Med Chem. 2014. PMID: 24721831 Free PMC article.

7

In vitro and in vivo characterization of two C-11-labeled pet tracers for vesicular acetylcholine transporter.

Padakanti PK, Zhang X, Jin H, Cui J, Wang R, Li J, Flores HP, Parsons SM, Perlmutter JS, Tu Z. Padakanti PK, et al. Among authors: flores hp. Mol Imaging Biol. 2014 Dec;16(6):773-80. doi: 10.1007/s11307-014-0749-9. Mol Imaging Biol. 2014. PMID: 24865402 Free PMC article.

8

Synthesis and biological characterization of a promising F-18 PET tracer for vesicular acetylcholine transporter.

Tu Z, Zhang X, Jin H, Yue X, Padakanti PK, Yu L, Liu H, Flores HP, Kaneshige K, Parsons SM, Perlmutter JS. Tu Z, et al. Among authors: flores hp. Bioorg Med Chem. 2015 Aug 1;23(15):4699-4709. doi: 10.1016/j.bmc.2015.05.058. Epub 2015 Jun 5. Bioorg Med Chem. 2015. PMID: 26138195 Free PMC article.

9

Chiral resolution of serial potent and selective σ₁ ligands and biological evaluation of (-)-[¹⁸F]TZ3108 in rodent and the nonhuman primate brain.

Yue X, Jin H, Luo Z, Liu H, Zhang X, McSpadden ED, Tian L, Flores HP, Perlmutter JS, Parsons SM, Tu Z. Yue X, et al. Among authors: flores hp. Bioorg Med Chem. 2017 Feb 15;25(4):1533-1542. doi: 10.1016/j.bmc.2017.01.017. Epub 2017 Jan 16. Bioorg Med Chem. 2017. PMID: 28129990 Free PMC article.

10

Synthesis, resolution, and in vitro evaluation of three vesicular acetylcholine transporter ligands and evaluation of the lead fluorine-18 radioligand in a nonhuman primate.

Yue X, Jin H, Liu H, Luo Z, Zhang X, Kaneshige K, Flores HP, Perlmutter JS, Parsons SM, Tu Z. Yue X, et al. Among authors: flores hp. Org Biomol Chem. 2017 Jun 21;15(24):5197-5209. doi: 10.1039/c7ob00854f. Org Biomol Chem. 2017. PMID: 28590490 Free PMC article.

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