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Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue.
Gerdes MJ, Sevinsky CJ, Sood A, Adak S, Bello MO, Bordwell A, Can A, Corwin A, Dinn S, Filkins RJ, Hollman D, Kamath V, Kaanumalle S, Kenny K, Larsen M, Lazare M, Li Q, Lowes C, McCulloch CC, McDonough E, Montalto MC, Pang Z, Rittscher J, Santamaria-Pang A, Sarachan BD, Seel ML, Seppo A, Shaikh K, Sui Y, Zhang J, Ginty F. Gerdes MJ, et al. Among authors: mcdonough e. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11982-7. doi: 10.1073/pnas.1300136110. Epub 2013 Jul 1. Proc Natl Acad Sci U S A. 2013. PMID: 23818604 Free PMC article.
Multiscale, multimodal analysis of tumor heterogeneity in IDH1 mutant vs wild-type diffuse gliomas.
Berens ME, Sood A, Barnholtz-Sloan JS, Graf JF, Cho S, Kim S, Kiefer J, Byron SA, Halperin RF, Nasser S, Adkins J, Cuyugan L, Devine K, Ostrom Q, Couce M, Wolansky L, McDonough E, Schyberg S, Dinn S, Sloan AE, Prados M, Phillips JJ, Nelson SJ, Liang WS, Al-Kofahi Y, Rusu M, Zavodszky MI, Ginty F. Berens ME, et al. Among authors: mcdonough e. PLoS One. 2019 Dec 27;14(12):e0219724. doi: 10.1371/journal.pone.0219724. eCollection 2019. PLoS One. 2019. PMID: 31881020 Free PMC article.
Quantitative patterns of motor cortex proteinopathy across ALS genotypes.
Nolan M, Scott C, Gamarallage MP, Lunn D, Carpenter K, McDonough E, Meyer D, Kaanumalle S, Santamaria-Pang A, Turner MR, Talbot K, Ansorge O. Nolan M, et al. Among authors: mcdonough e. Acta Neuropathol Commun. 2020 Jul 2;8(1):98. doi: 10.1186/s40478-020-00961-2. Acta Neuropathol Commun. 2020. PMID: 32616036 Free PMC article.
Multi-protein spatial signatures in ductal carcinoma in situ (DCIS) of breast.
Badve SS, Cho S, Gökmen-Polar Y, Sui Y, Chadwick C, McDonough E, Sood A, Taylor M, Zavodszky M, Tan PH, Gerdes M, Harris AL, Ginty F. Badve SS, et al. Among authors: mcdonough e. Br J Cancer. 2021 Mar;124(6):1150-1159. doi: 10.1038/s41416-020-01216-6. Epub 2021 Jan 7. Br J Cancer. 2021. PMID: 33414541 Free PMC article.
FLINO: a new method for immunofluorescence bioimage normalization.
Graf J, Cho S, McDonough E, Corwin A, Sood A, Lindner A, Salvucci M, Stachtea X, Van Schaeybroeck S, Dunne PD, Laurent-Puig P, Longley D, Prehn JHM, Ginty F. Graf J, et al. Among authors: mcdonough e. Bioinformatics. 2022 Jan 3;38(2):520-526. doi: 10.1093/bioinformatics/btab686. Bioinformatics. 2022. PMID: 34601553 Free PMC article.
Stratification of chemotherapy-treated stage III colorectal cancer patients using multiplexed imaging and single-cell analysis of T-cell populations.
Stachtea X, Loughrey MB, Salvucci M, Lindner AU, Cho S, McDonough E, Sood A, Graf J, Santamaria-Pang A, Corwin A, Laurent-Puig P, Dasgupta S, Shia J, Owens JR, Abate S, Van Schaeybroeck S, Lawler M, Prehn JHM, Ginty F, Longley DB. Stachtea X, et al. Among authors: mcdonough e. Mod Pathol. 2022 Apr;35(4):564-576. doi: 10.1038/s41379-021-00953-0. Epub 2021 Nov 3. Mod Pathol. 2022. PMID: 34732839 Free PMC article.
An atlas of inter- and intra-tumor heterogeneity of apoptosis competency in colorectal cancer tissue at single-cell resolution.
Lindner AU, Salvucci M, McDonough E, Cho S, Stachtea X, O'Connell EP, Corwin AD, Santamaria-Pang A, Carberry S, Fichtner M, Van Schaeybroeck S, Laurent-Puig P, Burke JP, McNamara DA, Lawler M, Sood A, Graf JF, Rehm M, Dunne PD, Longley DB, Ginty F, Prehn JHM. Lindner AU, et al. Among authors: mcdonough e. Cell Death Differ. 2022 Apr;29(4):806-817. doi: 10.1038/s41418-021-00895-9. Epub 2021 Nov 9. Cell Death Differ. 2022. PMID: 34754079 Free PMC article.
Spatial mapping of protein composition and tissue organization: a primer for multiplexed antibody-based imaging.
Hickey JW, Neumann EK, Radtke AJ, Camarillo JM, Beuschel RT, Albanese A, McDonough E, Hatler J, Wiblin AE, Fisher J, Croteau J, Small EC, Sood A, Caprioli RM, Angelo RM, Nolan GP, Chung K, Hewitt SM, Germain RN, Spraggins JM, Lundberg E, Snyder MP, Kelleher NL, Saka SK. Hickey JW, et al. Among authors: mcdonough e. Nat Methods. 2022 Mar;19(3):284-295. doi: 10.1038/s41592-021-01316-y. Epub 2021 Nov 22. Nat Methods. 2022. PMID: 34811556 Free PMC article. Review.
144 results