Melzig L - Search Results

1

Synthesis and structure-activity relationship studies of O-biphenyl-3-yl carbamates as peripherally restricted fatty acid amide hydrolase inhibitors.

Moreno-Sanz G, Duranti A, Melzig L, Fiorelli C, Ruda GF, Colombano G, Mestichelli P, Sanchini S, Tontini A, Mor M, Bandiera T, Scarpelli R, Tarzia G, Piomelli D. Moreno-Sanz G, et al. Among authors: melzig l. J Med Chem. 2013 Jul 25;56(14):5917-30. doi: 10.1021/jm4007017. Epub 2013 Jul 3. J Med Chem. 2013. PMID: 23822179 Free PMC article.

2

Benzoxazolone Carboxamides as Potent Acid Ceramidase Inhibitors: Synthesis and Structure-Activity Relationship (SAR) Studies.

Bach A, Pizzirani D, Realini N, Vozella V, Russo D, Penna I, Melzig L, Scarpelli R, Piomelli D. Bach A, et al. Among authors: melzig l. J Med Chem. 2015 Dec 10;58(23):9258-72. doi: 10.1021/acs.jmedchem.5b01188. Epub 2015 Nov 23. J Med Chem. 2015. PMID: 26560855

3

Direct aminoalkylation of arenes, heteroarenes, and alkenes via Ni-catalyzed Negishi cross-coupling reactions.

Melzig L, Dennenwaldt T, Gavryushin A, Knochel P. Melzig L, et al. J Org Chem. 2011 Nov 4;76(21):8891-906. doi: 10.1021/jo201630e. Epub 2011 Oct 4. J Org Chem. 2011. PMID: 21923124

4

Direct aminoalkylation of arenes and hetarenes via Ni-catalyzed Negishi cross-coupling reactions.

Melzig L, Gavryushin A, Knochel P. Melzig L, et al. Org Lett. 2007 Dec 20;9(26):5529-32. doi: 10.1021/ol702499h. Epub 2007 Nov 30. Org Lett. 2007. PMID: 18047363

5

Pd-catalyzed cross-coupling of functionalized organozinc reagents with thiomethyl-substituted heterocycles.

Metzger A, Melzig L, Despotopoulou C, Knochel P. Metzger A, et al. Among authors: melzig l. Org Lett. 2009 Sep 17;11(18):4228-31. doi: 10.1021/ol9017003. Org Lett. 2009. PMID: 19691353

6

Room temperature cross-coupling of highly functionalized organozinc reagents with thiomethylated N-heterocycles by nickel catalysis.

Melzig L, Metzger A, Knochel P. Melzig L, et al. J Org Chem. 2010 Mar 19;75(6):2131-3. doi: 10.1021/jo1001615. J Org Chem. 2010. PMID: 20192173

7

Pd- and Ni-catalyzed cross-coupling reactions of functionalized organozinc reagents with unsaturated thioethers.

Melzig L, Metzger A, Knochel P. Melzig L, et al. Chemistry. 2011 Mar 1;17(10):2948-56. doi: 10.1002/chem.201002850. Epub 2011 Jan 30. Chemistry. 2011. PMID: 21280109

8

Meta- and para-difunctionalization of arenes via a sulfoxide-magnesium exchange reaction.

Rauhut CB, Melzig L, Knochel P. Rauhut CB, et al. Among authors: melzig l. Org Lett. 2008 Sep 4;10(17):3891-4. doi: 10.1021/ol801431z. Epub 2008 Aug 5. Org Lett. 2008. PMID: 18680381

9

Difunctionalisation of arenes and heteroarenes by directed metallation and sulfoxide-magnesium exchange.

Melzig L, Rauhut CB, Naredi-Rainer N, Knochel P. Melzig L, et al. Chemistry. 2011 May 2;17(19):5362-72. doi: 10.1002/chem.201003657. Epub 2011 Apr 1. Chemistry. 2011. PMID: 21462274

10

Preparation of polyfunctional zinc organometallics using an Fe- or Co-catalyzed Cl/Zn-exchange.

Melzig L, Diène CR, Rohbogner CJ, Knochel P. Melzig L, et al. Org Lett. 2011 Jun 17;13(12):3174-7. doi: 10.1021/ol201100p. Epub 2011 May 19. Org Lett. 2011. PMID: 21595435

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