Gaughan L - Search Results

1

AZD3514: a small molecule that modulates androgen receptor signaling and function in vitro and in vivo.

Loddick SA, Ross SJ, Thomason AG, Robinson DM, Walker GE, Dunkley TP, Brave SR, Broadbent N, Stratton NC, Trueman D, Mouchet E, Shaheen FS, Jacobs VN, Cumberbatch M, Wilson J, Jones RD, Bradbury RH, Rabow A, Gaughan L, Womack C, Barry ST, Robson CN, Critchlow SE, Wedge SR, Brooks AN. Loddick SA, et al. Among authors: gaughan l. Mol Cancer Ther. 2013 Sep;12(9):1715-27. doi: 10.1158/1535-7163.MCT-12-1174. Epub 2013 Jul 16. Mol Cancer Ther. 2013. PMID: 23861347 Free PMC article.

2

Tip60 is a nuclear hormone receptor coactivator.

Brady ME, Ozanne DM, Gaughan L, Waite I, Cook S, Neal DE, Robson CN. Brady ME, et al. Among authors: gaughan l. J Biol Chem. 1999 Jun 18;274(25):17599-604. doi: 10.1074/jbc.274.25.17599. J Biol Chem. 1999. PMID: 10364196 Free article.

3

Androgen receptor nuclear translocation is facilitated by the f-actin cross-linking protein filamin.

Ozanne DM, Brady ME, Cook S, Gaughan L, Neal DE, Robson CN. Ozanne DM, et al. Among authors: gaughan l. Mol Endocrinol. 2000 Oct;14(10):1618-26. doi: 10.1210/mend.14.10.0541. Mol Endocrinol. 2000. PMID: 11043577

4

Tip60 is a co-activator specific for class I nuclear hormone receptors.

Gaughan L, Brady ME, Cook S, Neal DE, Robson CN. Gaughan L, et al. J Biol Chem. 2001 Dec 14;276(50):46841-8. doi: 10.1074/jbc.M103710200. Epub 2001 Oct 8. J Biol Chem. 2001. PMID: 11591700 Free article.

5

Tip60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptor.

Gaughan L, Logan IR, Cook S, Neal DE, Robson CN. Gaughan L, et al. J Biol Chem. 2002 Jul 19;277(29):25904-13. doi: 10.1074/jbc.M203423200. Epub 2002 May 6. J Biol Chem. 2002. PMID: 11994312 Free article.

6

Control of human PIRH2 protein stability: involvement of TIP60 and the proteosome.

Logan IR, Sapountzi V, Gaughan L, Neal DE, Robson CN. Logan IR, et al. Among authors: gaughan l. J Biol Chem. 2004 Mar 19;279(12):11696-704. doi: 10.1074/jbc.M312712200. Epub 2003 Dec 29. J Biol Chem. 2004. PMID: 14701804 Free article.

7

Upregulation and nuclear recruitment of HDAC1 in hormone refractory prostate cancer.

Halkidou K, Gaughan L, Cook S, Leung HY, Neal DE, Robson CN. Halkidou K, et al. Among authors: gaughan l. Prostate. 2004 May 1;59(2):177-89. doi: 10.1002/pros.20022. Prostate. 2004. PMID: 15042618

8

Regulation of androgen receptor and histone deacetylase 1 by Mdm2-mediated ubiquitylation.

Gaughan L, Logan IR, Neal DE, Robson CN. Gaughan L, et al. Nucleic Acids Res. 2005 Jan 7;33(1):13-26. doi: 10.1093/nar/gki141. Print 2005. Nucleic Acids Res. 2005. PMID: 15640443 Free PMC article.

9

Huntingtin interacting protein 1 modulates the transcriptional activity of nuclear hormone receptors.

Mills IG, Gaughan L, Robson C, Ross T, McCracken S, Kelly J, Neal DE. Mills IG, et al. Among authors: gaughan l. J Cell Biol. 2005 Jul 18;170(2):191-200. doi: 10.1083/jcb.200503106. J Cell Biol. 2005. PMID: 16027218 Free PMC article.

10

Human PIRH2 enhances androgen receptor signaling through inhibition of histone deacetylase 1 and is overexpressed in prostate cancer.

Logan IR, Gaughan L, McCracken SR, Sapountzi V, Leung HY, Robson CN. Logan IR, et al. Among authors: gaughan l. Mol Cell Biol. 2006 Sep;26(17):6502-10. doi: 10.1128/MCB.00147-06. Mol Cell Biol. 2006. PMID: 16914734 Free PMC article.

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