Castelli MP - Search Results

1

The new compound GET73, N-[(4-trifluoromethyl)benzyl]4-methoxybutyramide, Regulates hippocampal Aminoacidergic transmission possibly via an allosteric modulation of mGlu5 receptor. Behavioural evidence of its "anti-alcohol" and anxiolytic properties.

Ferraro L, Loche A, Beggiato S, Tomasini MC, Antonelli T, Colombo G, Lobina C, Carai MA, Porcu A, Castelli MP, Clerici F, Borelli AC, Cacciaglia R, Tanganelli S. Ferraro L, et al. Among authors: castelli mp. Curr Med Chem. 2013;20(27):3339-57. doi: 10.2174/09298673113209990167. Curr Med Chem. 2013. PMID: 23862615 Review.

2

Central effects of 1,4-butanediol are mediated by GABA(B) receptors via its conversion into gamma-hydroxybutyric acid.

Carai MA, Colombo G, Reali R, Serra S, Mocci I, Castelli MP, Cignarella G, Gessa GL. Carai MA, et al. Among authors: castelli mp. Eur J Pharmacol. 2002 Apr 26;441(3):157-63. doi: 10.1016/s0014-2999(02)01502-9. Eur J Pharmacol. 2002. PMID: 12063087

3

Selective gamma-hydroxybutyric acid receptor ligands increase extracellular glutamate in the hippocampus, but fail to activate G protein and to produce the sedative/hypnotic effect of gamma-hydroxybutyric acid.

Castelli MP, Ferraro L, Mocci I, Carta F, Carai MA, Antonelli T, Tanganelli S, Cignarella G, Gessa GL. Castelli MP, et al. J Neurochem. 2003 Nov;87(3):722-32. doi: 10.1046/j.1471-4159.2003.02037.x. J Neurochem. 2003. PMID: 14535954 Free article.

4

Up-regulation of GABA(B) receptors by chronic administration of the GABA(B) receptor antagonist SCH 50,911.

Pibiri F, Carboni G, Carai MA, Gessa GL, Castelli MP. Pibiri F, et al. Among authors: castelli mp. Eur J Pharmacol. 2005 May 16;515(1-3):94-8. doi: 10.1016/j.ejphar.2005.03.040. Eur J Pharmacol. 2005. PMID: 15893746

5

Differential G-protein coupling to GABAB receptor in limbic areas of alcohol-preferring and -nonpreferring rats.

Castelli MP, Pibiri F, Piras AP, Carboni G, Orrù A, Gessa GL, Carai MA, Colombo G. Castelli MP, et al. Eur J Pharmacol. 2005 Oct 31;523(1-3):67-70. doi: 10.1016/j.ejphar.2005.09.011. Epub 2005 Oct 13. Eur J Pharmacol. 2005. PMID: 16226245

6

Characterization of COR627 and COR628, two novel positive allosteric modulators of the GABA(B) receptor.

Castelli MP, Casu A, Casti P, Lobina C, Carai MA, Colombo G, Solinas M, Giunta D, Mugnaini C, Pasquini S, Tafi A, Brogi S, Gessa GL, Corelli F. Castelli MP, et al. J Pharmacol Exp Ther. 2012 Mar;340(3):529-38. doi: 10.1124/jpet.111.186460. Epub 2011 Nov 30. J Pharmacol Exp Ther. 2012. PMID: 22129594

7

Anti-Alcohol and Anxiolytic Properties of a New Chemical Entity, GET73.

Loche A, Simonetti F, Lobina C, Carai MA, Colombo G, Castelli MP, Barone D, Cacciaglia R. Loche A, et al. Among authors: castelli mp. Front Psychiatry. 2012 Feb 14;3:8. doi: 10.3389/fpsyt.2012.00008. eCollection 2012. Front Psychiatry. 2012. PMID: 22347868 Free PMC article.

8

Synthesis and pharmacological characterization of 2-(acylamino)thiophene derivatives as metabolically stable, orally effective, positive allosteric modulators of the GABAB receptor.

Mugnaini C, Pedani V, Casu A, Lobina C, Casti A, Maccioni P, Porcu A, Giunta D, Lamponi S, Solinas M, Dragoni S, Valoti M, Colombo G, Castelli MP, Gessa GL, Corelli F. Mugnaini C, et al. Among authors: castelli mp. J Med Chem. 2013 May 9;56(9):3620-35. doi: 10.1021/jm400144w. Epub 2013 Apr 18. J Med Chem. 2013. PMID: 23544432

9

In vitro and in vivo pharmacological characterization of SSD114, a novel GABAB positive allosteric modulator.

Porcu A, Lobina C, Giunta D, Solinas M, Mugnaini C, Castelli MP. Porcu A, et al. Among authors: castelli mp. Eur J Pharmacol. 2016 Nov 15;791:115-123. doi: 10.1016/j.ejphar.2016.08.032. Epub 2016 Aug 27. Eur J Pharmacol. 2016. PMID: 27578262

10

Suppressing effect of saikosaponin A, an active ingredient of Bupleurum falcatum, on chocolate self-administration and reinstatement of chocolate seeking in rats.

Lorrai I, Maccioni P, Carai MA, Capra A, Castelli MP, Riva A, Morazzoni P, Gessa GL, Colombo G. Lorrai I, et al. Among authors: castelli mp. Neurosci Lett. 2017 Jan 18;638:211-217. doi: 10.1016/j.neulet.2016.12.019. Epub 2016 Dec 19. Neurosci Lett. 2017. PMID: 28007642

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