Romero-Canelón I - Search Results

1

Next-generation metal anticancer complexes: multitargeting via redox modulation.

Romero-Canelón I, Sadler PJ. Romero-Canelón I, et al. Inorg Chem. 2013 Nov 4;52(21):12276-91. doi: 10.1021/ic400835n. Epub 2013 Jul 23. Inorg Chem. 2013. PMID: 23879584

2

Contrasting cellular uptake pathways for chlorido and iodido iminopyridine ruthenium arene anticancer complexes.

Romero-Canelón I, Pizarro AM, Habtemariam A, Sadler PJ. Romero-Canelón I, et al. Metallomics. 2012 Dec;4(12):1271-9. doi: 10.1039/c2mt20189e. Metallomics. 2012. PMID: 23138378

3

The contrasting activity of iodido versus chlorido ruthenium and osmium arene azo- and imino-pyridine anticancer complexes: control of cell selectivity, cross-resistance, p53 dependence, and apoptosis pathway.

Romero-Canelón I, Salassa L, Sadler PJ. Romero-Canelón I, et al. J Med Chem. 2013 Feb 14;56(3):1291-300. doi: 10.1021/jm3017442. Epub 2013 Jan 31. J Med Chem. 2013. PMID: 23368735 Free article.

4

Organometallic Iridium(III) anticancer complexes with new mechanisms of action: NCI-60 screening, mitochondrial targeting, and apoptosis.

Hearn JM, Romero-Canelón I, Qamar B, Liu Z, Hands-Portman I, Sadler PJ. Hearn JM, et al. ACS Chem Biol. 2013;8(6):1335-43. doi: 10.1021/cb400070a. Epub 2013 Apr 25. ACS Chem Biol. 2013. PMID: 23618382 Free PMC article.

5

The potent oxidant anticancer activity of organoiridium catalysts.

Liu Z, Romero-Canelón I, Qamar B, Hearn JM, Habtemariam A, Barry NP, Pizarro AM, Clarkson GJ, Sadler PJ. Liu Z, et al. Angew Chem Int Ed Engl. 2014 Apr 7;53(15):3941-6. doi: 10.1002/anie.201311161. Epub 2014 Mar 11. Angew Chem Int Ed Engl. 2014. PMID: 24616129 Free PMC article.

6

Potent organometallic osmium compounds induce mitochondria-mediated apoptosis and S-phase cell cycle arrest in A549 non-small cell lung cancer cells.

van Rijt SH, Romero-Canelón I, Fu Y, Shnyder SD, Sadler PJ. van Rijt SH, et al. Metallomics. 2014 May;6(5):1014-22. doi: 10.1039/c4mt00034j. Metallomics. 2014. PMID: 24668459 Free article.

7

Precious metal carborane polymer nanoparticles: characterisation of micellar formulations and anticancer activity.

Barry NP, Pitto-Barry A, Romero-Canelón I, Tran J, Soldevila-Barreda JJ, Hands-Portman I, Smith CJ, Kirby N, Dove AP, O'Reilly RK, Sadler PJ. Barry NP, et al. Faraday Discuss. 2014;175:229-40. doi: 10.1039/c4fd00098f. Faraday Discuss. 2014. PMID: 25270092

8

Transfer hydrogenation catalysis in cells as a new approach to anticancer drug design.

Soldevila-Barreda JJ, Romero-Canelón I, Habtemariam A, Sadler PJ. Soldevila-Barreda JJ, et al. Nat Commun. 2015 Mar 20;6:6582. doi: 10.1038/ncomms7582. Nat Commun. 2015. PMID: 25791197 Free PMC article.

9

Potent organo-osmium compound shifts metabolism in epithelial ovarian cancer cells.

Hearn JM, Romero-Canelón I, Munro AF, Fu Y, Pizarro AM, Garnett MJ, McDermott U, Carragher NO, Sadler PJ. Hearn JM, et al. Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):E3800-5. doi: 10.1073/pnas.1500925112. Epub 2015 Jul 10. Proc Natl Acad Sci U S A. 2015. PMID: 26162681 Free PMC article.

10

Enhancement of Selectivity of an Organometallic Anticancer Agent by Redox Modulation.

Romero-Canelón I, Mos M, Sadler PJ. Romero-Canelón I, et al. J Med Chem. 2015 Oct 8;58(19):7874-80. doi: 10.1021/acs.jmedchem.5b00655. Epub 2015 Sep 23. J Med Chem. 2015. PMID: 26397305 Free PMC article.

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