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Discovery and clinical translation of ceperognastat, an O-GlcNAcase (OGA) inhibitor, for the treatment of Alzheimer's disease.
Kielbasa W, Goldsmith P, Donnelly KB, Nuthall HN, Shcherbinin S, Fleisher AS, Hendle J, DuBois SL, Lowe SL, Zhang FF, Woerly EM, Dreyfus NJ, Evans D, Gilmore J, Mancini M, Constantinescu CC, Gunn RN, Russell DS, Collins EC, Brys M, Hutton ML, Mergott DJ. Kielbasa W, et al. Among authors: constantinescu cc. Alzheimers Dement (N Y). 2024 Dec 26;10(4):e70020. doi: 10.1002/trc2.70020. eCollection 2024 Oct-Dec. Alzheimers Dement (N Y). 2024. PMID: 39748851 Free PMC article.
Assessing disability progression using the WHODAS 2.0 in multiple sclerosis: Investigating clinical and socio-demographic factors in a large longitudinal cohort study (TONiC-MS).
Parker RMA, Tilling K, Mills R, Tennant A, Ben-Shlomo Y, Constantinescu CS, Kalra S, Young CA; TONiC Study Group. Parker RMA, et al. Among authors: constantinescu cs. Mult Scler Relat Disord. 2024 Dec 10;93:106228. doi: 10.1016/j.msard.2024.106228. Online ahead of print. Mult Scler Relat Disord. 2024. PMID: 39706109 Free article.
Longitudinal imaging of therapeutic enzyme expression after gene therapy for Fabry disease using positron emission tomography and the radiotracer [18F]AGAL.
Kaittanis C, Teceno T, Knight A, Petibon Y, Sandoval P, Cohen L, Ahn SH, Belanger AP, Clark LM, Nguyen QD, Ruangsiriluk W, Mukherji S, Constantinescu CC, Amenta AL, Narayanan S, Deshpande M, Islam R, Yuan S, McQuade P, Winkelmann CT, Lohith TG. Kaittanis C, et al. Among authors: constantinescu cc. Mol Ther. 2024 Nov 19:S1525-0016(24)00748-2. doi: 10.1016/j.ymthe.2024.11.021. Online ahead of print. Mol Ther. 2024. PMID: 39563031 Free article.
544 results