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Anticancer compound ABT-263 accelerates apoptosis in virus-infected cells and imbalances cytokine production and lowers survival rates of infected mice.
Kakkola L, Denisova OV, Tynell J, Viiliäinen J, Ysenbaert T, Matos RC, Nagaraj A, Ohman T, Kuivanen S, Paavilainen H, Feng L, Yadav B, Julkunen I, Vapalahti O, Hukkanen V, Stenman J, Aittokallio T, Verschuren EW, Ojala PM, Nyman T, Saelens X, Dzeyk K, Kainov DE. Kakkola L, et al. Cell Death Dis. 2013 Jul 25;4(7):e742. doi: 10.1038/cddis.2013.267. Cell Death Dis. 2013. PMID: 23887633 Free PMC article.
Emerging cellular targets for influenza antiviral agents.
Müller KH, Kakkola L, Nagaraj AS, Cheltsov AV, Anastasina M, Kainov DE. Müller KH, et al. Among authors: kakkola l. Trends Pharmacol Sci. 2012 Feb;33(2):89-99. doi: 10.1016/j.tips.2011.10.004. Epub 2011 Dec 22. Trends Pharmacol Sci. 2012. PMID: 22196854 Review.
Obatoclax, saliphenylhalamide, and gemcitabine inhibit influenza a virus infection.
Denisova OV, Kakkola L, Feng L, Stenman J, Nagaraj A, Lampe J, Yadav B, Aittokallio T, Kaukinen P, Ahola T, Kuivanen S, Vapalahti O, Kantele A, Tynell J, Julkunen I, Kallio-Kokko H, Paavilainen H, Hukkanen V, Elliott RM, De Brabander JK, Saelens X, Kainov DE. Denisova OV, et al. Among authors: kakkola l. J Biol Chem. 2012 Oct 12;287(42):35324-35332. doi: 10.1074/jbc.M112.392142. Epub 2012 Aug 21. J Biol Chem. 2012. PMID: 22910914 Free PMC article.
Molecular evolution and epidemiology of echovirus 6 in Finland.
Smura T, Kakkola L, Blomqvist S, Klemola P, Parsons A, Kallio-Kokko H, Savolainen-Kopra C, Kainov DE, Roivainen M. Smura T, et al. Among authors: kakkola l. Infect Genet Evol. 2013 Jun;16:234-47. doi: 10.1016/j.meegid.2013.02.011. Epub 2013 Feb 24. Infect Genet Evol. 2013. PMID: 23462388
Comparative Analysis of Whole-Genome Sequences of Influenza A(H1N1)pdm09 Viruses Isolated from Hospitalized and Nonhospitalized Patients Identifies Missense Mutations That Might Be Associated with Patient Hospital Admissions in Finland during 2009 to 2014.
Mishel P, Ojala T, Benner C, Lakspere T, Bychkov D, Jalovaara P, Kakkola L, Kallio-Kokko H, Kantele A, Kankainen M, Ikonen N, Ripatti S, Julkunen I, Kainov DE. Mishel P, et al. Among authors: kakkola l. Genome Announc. 2015 Jul 30;3(4):e00676-15. doi: 10.1128/genomeA.00676-15. Genome Announc. 2015. PMID: 26227588 Free PMC article.
58 results