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The allelic variant of LAR gene promoter -127 bp T-->A is associated with reduced risk of obesity and other features related to insulin resistance.
Miscio G, Tassi V, Coco A, Soccio T, Di Paola R, Prudente S, Baratta R, Frittitta L, Ludovico O, Padovano L, Dallapiccola B, Di Mario U, De Cosmo S, Trischitta V. Miscio G, et al. Among authors: prudente s. J Mol Med (Berl). 2004 Jul;82(7):459-66. doi: 10.1007/s00109-004-0544-1. Epub 2004 May 19. J Mol Med (Berl). 2004. PMID: 15150650
The K121Q polymorphism of the ENPP1/PC-1 gene is associated with insulin resistance/atherogenic phenotypes, including earlier onset of type 2 diabetes and myocardial infarction.
Bacci S, Ludovico O, Prudente S, Zhang YY, Di Paola R, Mangiacotti D, Rauseo A, Nolan D, Duffy J, Fini G, Salvemini L, Amico C, Vigna C, Pellegrini F, Menzaghi C, Doria A, Trischitta V. Bacci S, et al. Among authors: prudente s. Diabetes. 2005 Oct;54(10):3021-5. doi: 10.2337/diabetes.54.10.3021. Diabetes. 2005. PMID: 16186408
ENPP1 gene, insulin resistance and related clinical outcomes.
Bacci S, De Cosmo S, Prudente S, Trischitta V. Bacci S, et al. Among authors: prudente s. Curr Opin Clin Nutr Metab Care. 2007 Jul;10(4):403-9. doi: 10.1097/MCO.0b013e3281e386c9. Curr Opin Clin Nutr Metab Care. 2007. PMID: 17563456 Review.
83 results