Cihlar T - Search Results

1

Evaluation of the effect of cobicistat on the in vitro renal transport and cytotoxicity potential of tenofovir.

Stray KM, Bam RA, Birkus G, Hao J, Lepist EI, Yant SR, Ray AS, Cihlar T. Stray KM, et al. Among authors: cihlar t. Antimicrob Agents Chemother. 2013 Oct;57(10):4982-9. doi: 10.1128/AAC.00712-13. Epub 2013 Jul 29. Antimicrob Agents Chemother. 2013. PMID: 23896476 Free PMC article.

2

Transport of 9-(2-phosphonomethoxyethyl)adenine across plasma membrane of HeLa S3 cells is protein mediated.

Cihlár T, Rosenberg I, Votruba I, Holý A. Cihlár T, et al. Antimicrob Agents Chemother. 1995 Jan;39(1):117-24. doi: 10.1128/AAC.39.1.117. Antimicrob Agents Chemother. 1995. PMID: 7695292 Free PMC article.

3

Conversion of 1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl]cytosine to cidofovir by an intracellular cyclic CMP phosphodiesterase.

Mendel DB, Cihlar T, Moon K, Chen MS. Mendel DB, et al. Among authors: cihlar t. Antimicrob Agents Chemother. 1997 Mar;41(3):641-6. doi: 10.1128/AAC.41.3.641. Antimicrob Agents Chemother. 1997. PMID: 9056007 Free PMC article.

4

Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1.

Ho ES, Lin DC, Mendel DB, Cihlar T. Ho ES, et al. Among authors: cihlar t. J Am Soc Nephrol. 2000 Mar;11(3):383-393. doi: 10.1681/ASN.V113383. J Am Soc Nephrol. 2000. PMID: 10703662

5

Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1.

Mulato AS, Ho ES, Cihlar T. Mulato AS, et al. Among authors: cihlar t. J Pharmacol Exp Ther. 2000 Oct;295(1):10-5. J Pharmacol Exp Ther. 2000. PMID: 10991954

6

Assessment of mitochondrial toxicity in human cells treated with tenofovir: comparison with other nucleoside reverse transcriptase inhibitors.

Birkus G, Hitchcock MJ, Cihlar T. Birkus G, et al. Among authors: cihlar t. Antimicrob Agents Chemother. 2002 Mar;46(3):716-23. doi: 10.1128/AAC.46.3.716-723.2002. Antimicrob Agents Chemother. 2002. PMID: 11850253 Free PMC article.

7

Tenofovir exhibits low cytotoxicity in various human cell types: comparison with other nucleoside reverse transcriptase inhibitors.

Cihlar T, Birkus G, Greenwalt DE, Hitchcock MJ. Cihlar T, et al. Antiviral Res. 2002 Apr;54(1):37-45. doi: 10.1016/s0166-3542(01)00210-8. Antiviral Res. 2002. PMID: 11888656

8

Comparative effects of adefovir and selected nucleoside inhibitors of hepatitis B virus DNA polymerase on mitochondrial DNA in liver and skeletal muscle cells.

Birkus G, Gibbs CS, Cihlar T. Birkus G, et al. Among authors: cihlar t. J Viral Hepat. 2003 Jan;10(1):50-4. doi: 10.1046/j.1365-2893.2003.00399.x. J Viral Hepat. 2003. PMID: 12558912

9

Selective intracellular activation of a novel prodrug of the human immunodeficiency virus reverse transcriptase inhibitor tenofovir leads to preferential distribution and accumulation in lymphatic tissue.

Lee WA, He GX, Eisenberg E, Cihlar T, Swaminathan S, Mulato A, Cundy KC. Lee WA, et al. Among authors: cihlar t. Antimicrob Agents Chemother. 2005 May;49(5):1898-906. doi: 10.1128/AAC.49.5.1898-1906.2005. Antimicrob Agents Chemother. 2005. PMID: 15855512 Free PMC article.

10

Small molecules VP-14637 and JNJ-2408068 inhibit respiratory syncytial virus fusion by similar mechanisms.

Douglas JL, Panis ML, Ho E, Lin KY, Krawczyk SH, Grant DM, Cai R, Swaminathan S, Chen X, Cihlar T. Douglas JL, et al. Among authors: cihlar t. Antimicrob Agents Chemother. 2005 Jun;49(6):2460-6. doi: 10.1128/AAC.49.6.2460-2466.2005. Antimicrob Agents Chemother. 2005. PMID: 15917547 Free PMC article.

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