Floor SN - Search Results

1

Active site conformational dynamics are coupled to catalysis in the mRNA decapping enzyme Dcp2.

Aglietti RA, Floor SN, McClendon CL, Jacobson MP, Gross JD. Aglietti RA, et al. Among authors: floor sn. Structure. 2013 Sep 3;21(9):1571-80. doi: 10.1016/j.str.2013.06.021. Epub 2013 Aug 1. Structure. 2013. PMID: 23911090 Free PMC article.

2

IGHMBP2 deletion suppresses translation and activates the integrated stress response.

Park JE, Desai H, Liboy-Lugo J, Gu S, Jowhar Z, Xu A, Floor SN. Park JE, et al. Among authors: floor sn. bioRxiv [Preprint]. 2023 Dec 12:2023.12.11.571166. doi: 10.1101/2023.12.11.571166. bioRxiv. 2023. Update in: Life Sci Alliance. 2024 May 21;7(8):e202302554. doi: 10.26508/lsa.202302554 PMID: 38168189 Free PMC article. Updated. Preprint.

3

Dynamic regulation of messenger RNA structure controls translation.

Lin Y, Floor SN. Lin Y, et al. Among authors: floor sn. Nature. 2023 Sep;621(7978):259-260. doi: 10.1038/d41586-023-02673-8. Nature. 2023. PMID: 37674086 No abstract available.

4

A novel reporter for helicase activity in translation uncovers DDX3X interactions.

Wilkins KC, Schroeder T, Gu S, Revalde JL, Floor SN. Wilkins KC, et al. Among authors: floor sn. RNA. 2024 Jul 16;30(8):1041-1057. doi: 10.1261/rna.079837.123. RNA. 2024. PMID: 38697667 Free PMC article.

5

Protein-protein interactions with G3BPs drive stress granule condensation and gene expression changes under cellular stress.

Liboy-Lugo JM, Espinoza CA, Sheu-Gruttadauria J, Park JE, Xu A, Jowhar Z, Gao AL, Carmona-Negrón JA, Wittmann T, Jura N, Floor SN. Liboy-Lugo JM, et al. Among authors: floor sn. bioRxiv [Preprint]. 2024 Feb 7:2024.02.06.579149. doi: 10.1101/2024.02.06.579149. bioRxiv. 2024. PMID: 38370785 Free PMC article. Preprint.

6

mRNA decapping is promoted by an RNA-binding channel in Dcp2.

Deshmukh MV, Jones BN, Quang-Dang DU, Flinders J, Floor SN, Kim C, Jemielity J, Kalek M, Darzynkiewicz E, Gross JD. Deshmukh MV, et al. Among authors: floor sn. Mol Cell. 2008 Feb 15;29(3):324-36. doi: 10.1016/j.molcel.2007.11.027. Mol Cell. 2008. PMID: 18280238 Free article.

7

Control of mRNA decapping by Dcp2: An open and shut case?

Floor SN, Jones BN, Gross JD. Floor SN, et al. RNA Biol. 2008 Oct-Dec;5(4):189-92. doi: 10.4161/rna.6859. Epub 2008 Oct 26. RNA Biol. 2008. PMID: 18971632 Free PMC article.

8

Ligand-induced conformational heterogeneity of cytochrome P450 CYP119 identified by 2D NMR spectroscopy with the unnatural amino acid (13)C-p-methoxyphenylalanine.

Lampe JN, Floor SN, Gross JD, Nishida CR, Jiang Y, Trnka MJ, Ortiz de Montellano PR. Lampe JN, et al. Among authors: floor sn. J Am Chem Soc. 2008 Dec 3;130(48):16168-9. doi: 10.1021/ja8071463. J Am Chem Soc. 2008. PMID: 18998650 Free PMC article.

9

SRP RNA controls a conformational switch regulating the SRP-SRP receptor interaction.

Neher SB, Bradshaw N, Floor SN, Gross JD, Walter P. Neher SB, et al. Among authors: floor sn. Nat Struct Mol Biol. 2008 Sep;15(9):916-23. doi: 10.1038/nsmb.1467. Nat Struct Mol Biol. 2008. PMID: 19172744 Free PMC article.

10

A split active site couples cap recognition by Dcp2 to activation.

Floor SN, Jones BN, Hernandez GA, Gross JD. Floor SN, et al. Nat Struct Mol Biol. 2010 Sep;17(9):1096-101. doi: 10.1038/nsmb.1879. Epub 2010 Aug 15. Nat Struct Mol Biol. 2010. PMID: 20711189 Free PMC article.

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