Williams SL - Search Results

1

Specific elimination of mutant mitochondrial genomes in patient-derived cells by mitoTALENs.

Bacman SR, Williams SL, Pinto M, Peralta S, Moraes CT. Bacman SR, et al. Among authors: williams sl. Nat Med. 2013 Sep;19(9):1111-3. doi: 10.1038/nm.3261. Epub 2013 Aug 4. Nat Med. 2013. PMID: 23913125 Free PMC article.

2

Microdissection and analytical PCR for the investigation of mtDNA lesions.

Williams SL, Moraes CT. Williams SL, et al. Methods Cell Biol. 2007;80:481-501. doi: 10.1016/S0091-679X(06)80024-5. Methods Cell Biol. 2007. PMID: 17445710 Review. No abstract available.

3

Modulating mtDNA heteroplasmy by mitochondria-targeted restriction endonucleases in a 'differential multiple cleavage-site' model.

Bacman SR, Williams SL, Hernandez D, Moraes CT. Bacman SR, et al. Among authors: williams sl. Gene Ther. 2007 Sep;14(18):1309-18. doi: 10.1038/sj.gt.3302981. Epub 2007 Jun 28. Gene Ther. 2007. PMID: 17597792 Free PMC article.

4

Intra- and inter-molecular recombination of mitochondrial DNA after in vivo induction of multiple double-strand breaks.

Bacman SR, Williams SL, Moraes CT. Bacman SR, et al. Among authors: williams sl. Nucleic Acids Res. 2009 Jul;37(13):4218-26. doi: 10.1093/nar/gkp348. Epub 2009 May 12. Nucleic Acids Res. 2009. PMID: 19435881 Free PMC article.

5

In vivo methylation of mtDNA reveals the dynamics of protein-mtDNA interactions.

Rebelo AP, Williams SL, Moraes CT. Rebelo AP, et al. Among authors: williams sl. Nucleic Acids Res. 2009 Nov;37(20):6701-15. doi: 10.1093/nar/gkp727. Epub 2009 Sep 9. Nucleic Acids Res. 2009. PMID: 19740762 Free PMC article.

6

Organ-specific shifts in mtDNA heteroplasmy following systemic delivery of a mitochondria-targeted restriction endonuclease.

Bacman SR, Williams SL, Garcia S, Moraes CT. Bacman SR, et al. Among authors: williams sl. Gene Ther. 2010 Jun;17(6):713-20. doi: 10.1038/gt.2010.25. Epub 2010 Mar 11. Gene Ther. 2010. PMID: 20220783 Free PMC article.

7

Emerging therapeutic approaches to mitochondrial diseases.

Wenz T, Williams SL, Bacman SR, Moraes CT. Wenz T, et al. Among authors: williams sl. Dev Disabil Res Rev. 2010;16(2):219-29. doi: 10.1002/ddrr.109. Dev Disabil Res Rev. 2010. PMID: 20818736 Review.

8

The mtDNA mutation spectrum of the progeroid Polg mutator mouse includes abundant control region multimers.

Williams SL, Huang J, Edwards YJ, Ulloa RH, Dillon LM, Prolla TA, Vance JM, Moraes CT, Züchner S. Williams SL, et al. Cell Metab. 2010 Dec 1;12(6):675-82. doi: 10.1016/j.cmet.2010.11.012. Cell Metab. 2010. PMID: 21109200 Free PMC article.

9

Manipulation of mtDNA heteroplasmy in all striated muscles of newborn mice by AAV9-mediated delivery of a mitochondria-targeted restriction endonuclease.

Bacman SR, Williams SL, Duan D, Moraes CT. Bacman SR, et al. Among authors: williams sl. Gene Ther. 2012 Nov;19(11):1101-6. doi: 10.1038/gt.2011.196. Epub 2011 Dec 1. Gene Ther. 2012. PMID: 22130448 Free PMC article.

10

Increased mitochondrial biogenesis in muscle improves aging phenotypes in the mtDNA mutator mouse.

Dillon LM, Williams SL, Hida A, Peacock JD, Prolla TA, Lincoln J, Moraes CT. Dillon LM, et al. Among authors: williams sl. Hum Mol Genet. 2012 May 15;21(10):2288-97. doi: 10.1093/hmg/dds049. Epub 2012 Feb 21. Hum Mol Genet. 2012. PMID: 22357654 Free PMC article.

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