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Vesicular and non-vesicular transport feed distinct glycosylation pathways in the Golgi.
D'Angelo G, Uemura T, Chuang CC, Polishchuk E, Santoro M, Ohvo-Rekilä H, Sato T, Di Tullio G, Varriale A, D'Auria S, Daniele T, Capuani F, Johannes L, Mattjus P, Monti M, Pucci P, Williams RL, Burke JE, Platt FM, Harada A, De Matteis MA. D'Angelo G, et al. Among authors: johannes l. Nature. 2013 Sep 5;501(7465):116-20. doi: 10.1038/nature12423. Epub 2013 Aug 4. Nature. 2013. PMID: 23913272
The association of Shiga-like toxin with detergent-resistant membranes is modulated by glucosylceramide and is an essential requirement in the endoplasmic reticulum for a cytotoxic effect.
Smith DC, Sillence DJ, Falguières T, Jarvis RM, Johannes L, Lord JM, Platt FM, Roberts LM. Smith DC, et al. Among authors: johannes l. Mol Biol Cell. 2006 Mar;17(3):1375-87. doi: 10.1091/mbc.e05-11-1035. Epub 2005 Dec 28. Mol Biol Cell. 2006. PMID: 16381816 Free PMC article.
Glycosphingolipid metabolic reprogramming drives neural differentiation.
Russo D, Della Ragione F, Rizzo R, Sugiyama E, Scalabrì F, Hori K, Capasso S, Sticco L, Fioriniello S, De Gregorio R, Granata I, Guarracino MR, Maglione V, Johannes L, Bellenchi GC, Hoshino M, Setou M, D'Esposito M, Luini A, D'Angelo G. Russo D, et al. Among authors: johannes l. EMBO J. 2018 Apr 3;37(7):e97674. doi: 10.15252/embj.201797674. Epub 2017 Dec 27. EMBO J. 2018. PMID: 29282205 Free PMC article.
The SNXy flavours of endosomal sorting.
Johannes L, Wunder C. Johannes L, et al. Nat Cell Biol. 2011 Jul 3;13(8):884-6. doi: 10.1038/ncb2300. Nat Cell Biol. 2011. PMID: 21725318
Galectin-3 drives glycosphingolipid-dependent biogenesis of clathrin-independent carriers.
Lakshminarayan R, Wunder C, Becken U, Howes MT, Benzing C, Arumugam S, Sales S, Ariotti N, Chambon V, Lamaze C, Loew D, Shevchenko A, Gaus K, Parton RG, Johannes L. Lakshminarayan R, et al. Among authors: johannes l. Nat Cell Biol. 2014 Jun;16(6):595-606. doi: 10.1038/ncb2970. Epub 2014 May 18. Nat Cell Biol. 2014. PMID: 24837829
Repurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype.
Soldati C, Lopez-Fabuel I, Wanderlingh LG, Garcia-Macia M, Monfregola J, Esposito A, Napolitano G, Guevara-Ferrer M, Scotto Rosato A, Krogsaeter EK, Paquet D, Grimm CM, Montefusco S, Braulke T, Storch S, Mole SE, De Matteis MA, Ballabio A, Sampaio JL, McKay T, Johannes L, Bolaños JP, Medina DL. Soldati C, et al. Among authors: johannes l. EMBO Mol Med. 2021 Oct 7;13(10):e13742. doi: 10.15252/emmm.202013742. Epub 2021 Aug 19. EMBO Mol Med. 2021. PMID: 34411438 Free PMC article.
TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann-Pick type C1, and Batten disease.
Scotto Rosato A, Krogsaeter EK, Jaślan D, Abrahamian C, Montefusco S, Soldati C, Spix B, Pizzo MT, Grieco G, Böck J, Wyatt A, Wünkhaus D, Passon M, Stieglitz M, Keller M, Hermey G, Markmann S, Gruber-Schoffnegger D, Cotman S, Johannes L, Crusius D, Boehm U, Wahl-Schott C, Biel M, Bracher F, De Leonibus E, Polishchuk E, Medina DL, Paquet D, Grimm C. Scotto Rosato A, et al. Among authors: johannes l. EMBO Mol Med. 2022 Sep 7;14(9):e15377. doi: 10.15252/emmm.202115377. Epub 2022 Aug 5. EMBO Mol Med. 2022. PMID: 35929194 Free PMC article.
Measuring retrograde transport to the trans-Golgi network.
Amessou M, Popoff V, Yelamos B, Saint-Pol A, Johannes L. Amessou M, et al. Among authors: johannes l. Curr Protoc Cell Biol. 2006 Oct;Chapter 15:Unit 15.10. doi: 10.1002/0471143030.cb1510s32. Curr Protoc Cell Biol. 2006. PMID: 18228477
229 results