Mak SK - Search Results

1

Mitochondrial dysfunction in skin fibroblasts from a Parkinson's disease patient with an alpha-synuclein triplication.

Mak SK, Tewari D, Tetrud JW, Langston JW, Schüle B. Mak SK, et al. J Parkinsons Dis. 2011;1(2):175-83. doi: 10.3233/JPD-2011-11025. J Parkinsons Dis. 2011. PMID: 23934919

2

LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: reversal by gene correction.

Sanders LH, Laganière J, Cooper O, Mak SK, Vu BJ, Huang YA, Paschon DE, Vangipuram M, Sundararajan R, Urnov FD, Langston JW, Gregory PD, Zhang HS, Greenamyre JT, Isacson O, Schüle B. Sanders LH, et al. Among authors: mak sk. Neurobiol Dis. 2014 Feb;62:381-6. doi: 10.1016/j.nbd.2013.10.013. Epub 2013 Oct 19. Neurobiol Dis. 2014. PMID: 24148854 Free PMC article.

3

Higher vulnerability and stress sensitivity of neuronal precursor cells carrying an alpha-synuclein gene triplication.

Flierl A, Oliveira LM, Falomir-Lockhart LJ, Mak SK, Hesley J, Soldner F, Arndt-Jovin DJ, Jaenisch R, Langston JW, Jovin TM, Schüle B. Flierl A, et al. Among authors: mak sk. PLoS One. 2014 Nov 12;9(11):e112413. doi: 10.1371/journal.pone.0112413. eCollection 2014. PLoS One. 2014. PMID: 25390032 Free PMC article.

4

Decreased alpha-synuclein expression in the aging mouse substantia nigra.

Mak SK, McCormack AL, Langston JW, Kordower JH, Di Monte DA. Mak SK, et al. Exp Neurol. 2009 Dec;220(2):359-65. doi: 10.1016/j.expneurol.2009.09.021. Epub 2009 Oct 1. Exp Neurol. 2009. PMID: 19800328

5

Small molecules greatly improve conversion of human-induced pluripotent stem cells to the neuronal lineage.

Mak SK, Huang YA, Iranmanesh S, Vangipuram M, Sundararajan R, Nguyen L, Langston JW, Schüle B. Mak SK, et al. Stem Cells Int. 2012;2012:140427. doi: 10.1155/2012/140427. Epub 2012 Apr 10. Stem Cells Int. 2012. PMID: 22567022 Free PMC article.

6

Lysosomal degradation of alpha-synuclein in vivo.

Mak SK, McCormack AL, Manning-Bog AB, Cuervo AM, Di Monte DA. Mak SK, et al. J Biol Chem. 2010 Apr 30;285(18):13621-9. doi: 10.1074/jbc.M109.074617. Epub 2010 Mar 3. J Biol Chem. 2010. PMID: 20200163 Free PMC article.

7

Pathologic modifications of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated squirrel monkeys.

McCormack AL, Mak SK, Shenasa M, Langston WJ, Forno LS, Di Monte DA. McCormack AL, et al. Among authors: mak sk. J Neuropathol Exp Neurol. 2008 Aug;67(8):793-802. doi: 10.1097/NEN.0b013e318180f0bd. J Neuropathol Exp Neurol. 2008. PMID: 18648323 Free PMC article.

8

Alpha-synuclein suppression by targeted small interfering RNA in the primate substantia nigra.

McCormack AL, Mak SK, Henderson JM, Bumcrot D, Farrer MJ, Di Monte DA. McCormack AL, et al. Among authors: mak sk. PLoS One. 2010 Aug 11;5(8):e12122. doi: 10.1371/journal.pone.0012122. PLoS One. 2010. PMID: 20711464 Free PMC article.

9

Neuroinflammation and α-synuclein accumulation in response to glucocerebrosidase deficiency are accompanied by synaptic dysfunction.

Ginns EI, Mak SK, Ko N, Karlgren J, Akbarian S, Chou VP, Guo Y, Lim A, Samuelsson S, LaMarca ML, Vazquez-DeRose J, Manning-Boğ AB. Ginns EI, et al. Among authors: mak sk. Mol Genet Metab. 2014 Feb;111(2):152-62. doi: 10.1016/j.ymgme.2013.12.003. Epub 2013 Dec 11. Mol Genet Metab. 2014. PMID: 24388731

10

Increased α-synuclein phosphorylation and nitration in the aging primate substantia nigra.

McCormack AL, Mak SK, Di Monte DA. McCormack AL, et al. Among authors: mak sk. Cell Death Dis. 2012 May 31;3(5):e315. doi: 10.1038/cddis.2012.50. Cell Death Dis. 2012. PMID: 22647852 Free PMC article.

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