Hwee DT - Search Results

1

Maintenance of muscle mass and load-induced growth in Muscle RING Finger 1 null mice with age.

Hwee DT, Baehr LM, Philp A, Baar K, Bodine SC. Hwee DT, et al. Aging Cell. 2014 Feb;13(1):92-101. doi: 10.1111/acel.12150. Epub 2013 Sep 12. Aging Cell. 2014. PMID: 23941502 Free PMC article.

2

Age-related deficit in load-induced skeletal muscle growth.

Hwee DT, Bodine SC. Hwee DT, et al. J Gerontol A Biol Sci Med Sci. 2009 Jun;64(6):618-28. doi: 10.1093/gerona/glp026. Epub 2009 Apr 7. J Gerontol A Biol Sci Med Sci. 2009. PMID: 19351696 Free PMC article.

3

Cardiac proteasome activity in muscle ring finger-1 null mice at rest and following synthetic glucocorticoid treatment.

Hwee DT, Gomes AV, Bodine SC. Hwee DT, et al. Am J Physiol Endocrinol Metab. 2011 Nov;301(5):E967-77. doi: 10.1152/ajpendo.00165.2011. Epub 2011 Aug 9. Am J Physiol Endocrinol Metab. 2011. PMID: 21828340 Free PMC article.

4

Complex I-associated hydrogen peroxide production is decreased and electron transport chain enzyme activities are altered in n-3 enriched fat-1 mice.

Hagopian K, Weber KL, Hwee DT, Van Eenennaam AL, López-Lluch G, Villalba JM, Burón I, Navas P, German JB, Watkins SM, Chen Y, Wei A, McDonald RB, Ramsey JJ. Hagopian K, et al. Among authors: hwee dt. PLoS One. 2010 Sep 13;5(9):e12696. doi: 10.1371/journal.pone.0012696. PLoS One. 2010. PMID: 20856881 Free PMC article.

5

The Ca²⁺ sensitizer CK-2066260 increases myofibrillar Ca²⁺ sensitivity and submaximal force selectively in fast skeletal muscle.

Hwee DT, Cheng AJ, Hartman JJ, Hinken AC, Lee K, Durham N, Russell AJ, Malik FI, Westerblad H, Jasper JR. Hwee DT, et al. J Physiol. 2017 Mar 1;595(5):1657-1670. doi: 10.1113/JP273248. Epub 2017 Jan 24. J Physiol. 2017. PMID: 27869319 Free PMC article.

6

Fast skeletal muscle troponin activator CK-2066260 mitigates skeletal muscle weakness independently of the underlying cause.

Cheng AJ, Ström J, Hwee DT, Malik FI, Westerblad H. Cheng AJ, et al. Among authors: hwee dt. J Cachexia Sarcopenia Muscle. 2020 Dec;11(6):1747-1757. doi: 10.1002/jcsm.12624. Epub 2020 Sep 21. J Cachexia Sarcopenia Muscle. 2020. PMID: 32954682 Free PMC article.

7

Fast skeletal muscle troponin activator CK-2066260 increases fatigue resistance by reducing the energetic cost of muscle contraction.

Cheng AJ, Hwee DT, Kim LH, Durham N, Yang HT, Hinken AC, Kennedy AR, Terjung RL, Jasper JR, Malik FI, Westerblad H. Cheng AJ, et al. Among authors: hwee dt. J Physiol. 2019 Sep;597(17):4615-4625. doi: 10.1113/JP278235. Epub 2019 Jul 17. J Physiol. 2019. PMID: 31246276 Free PMC article.

8

Fast skeletal muscle troponin activator tirasemtiv increases muscle function and performance in the B6SJL-SOD1G93A ALS mouse model.

Hwee DT, Kennedy A, Ryans J, Russell AJ, Jia Z, Hinken AC, Morgans DJ, Malik FI, Jasper JR. Hwee DT, et al. PLoS One. 2014 May 7;9(5):e96921. doi: 10.1371/journal.pone.0096921. eCollection 2014. PLoS One. 2014. PMID: 24805850 Free PMC article.

9

Acute and chronic tirasemtiv treatment improves in vivo and in vitro muscle performance in actin-based nemaline myopathy mice.

de Winter JM, Gineste C, Minardi E, Brocca L, Rossi M, Borsboom T, Beggs AH, Bernard M, Bendahan D, Hwee DT, Malik FI, Pellegrino MA, Bottinelli R, Gondin J, Ottenheijm CAC. de Winter JM, et al. Among authors: hwee dt. Hum Mol Genet. 2021 Jun 26;30(14):1305-1320. doi: 10.1093/hmg/ddab112. Hum Mol Genet. 2021. PMID: 33909041 Free PMC article.

10

The small-molecule fast skeletal troponin activator, CK-2127107, improves exercise tolerance in a rat model of heart failure.

Hwee DT, Kennedy AR, Hartman JJ, Ryans J, Durham N, Malik FI, Jasper JR. Hwee DT, et al. J Pharmacol Exp Ther. 2015 Apr;353(1):159-68. doi: 10.1124/jpet.114.222224. Epub 2015 Feb 12. J Pharmacol Exp Ther. 2015. PMID: 25678535

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