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Page 1
Canonical Wnt signaling negatively modulates regulatory T cell function.
van Loosdregt J, Fleskens V, Tiemessen MM, Mokry M, van Boxtel R, Meerding J, Pals CE, Kurek D, Baert MR, Delemarre EM, Gröne A, Koerkamp MJ, Sijts AJ, Nieuwenhuis EE, Maurice MM, van Es JH, Ten Berge D, Holstege FC, Staal FJ, Zaiss DM, Prakken BJ, Coffer PJ. van Loosdregt J, et al. Among authors: pals ce. Immunity. 2013 Aug 22;39(2):298-310. doi: 10.1016/j.immuni.2013.07.019. Epub 2013 Aug 15. Immunity. 2013. PMID: 23954131 Free article.
Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity.
van Loosdregt J, Fleskens V, Fu J, Brenkman AB, Bekker CP, Pals CE, Meerding J, Berkers CR, Barbi J, Gröne A, Sijts AJ, Maurice MM, Kalkhoven E, Prakken BJ, Ovaa H, Pan F, Zaiss DM, Coffer PJ. van Loosdregt J, et al. Among authors: pals ce. Immunity. 2013 Aug 22;39(2):259-71. doi: 10.1016/j.immuni.2013.05.018. Immunity. 2013. PMID: 23973222 Free PMC article.
Rapid temporal control of Foxp3 protein degradation by sirtuin-1.
van Loosdregt J, Brunen D, Fleskens V, Pals CE, Lam EW, Coffer PJ. van Loosdregt J, et al. Among authors: pals ce. PLoS One. 2011 Apr 20;6(4):e19047. doi: 10.1371/journal.pone.0019047. PLoS One. 2011. PMID: 21533107 Free PMC article.
Modulation of glutamine metabolism by the PI(3)K-PKB-FOXO network regulates autophagy.
van der Vos KE, Eliasson P, Proikas-Cezanne T, Vervoort SJ, van Boxtel R, Putker M, van Zutphen IJ, Mauthe M, Zellmer S, Pals C, Verhagen LP, Groot Koerkamp MJ, Braat AK, Dansen TB, Holstege FC, Gebhardt R, Burgering BM, Coffer PJ. van der Vos KE, et al. Nat Cell Biol. 2012 Aug;14(8):829-37. doi: 10.1038/ncb2536. Epub 2012 Jul 22. Nat Cell Biol. 2012. PMID: 22820375
FOXP3 can modulate TAL1 transcriptional activity through interaction with LMO2.
Fleskens V, Mokry M, van der Leun AM, Huppelschoten S, Pals CE, Peeters J, Coenen S, Cardoso BA, Barata JT, van Loosdregt J, Coffer PJ. Fleskens V, et al. Among authors: pals ce. Oncogene. 2016 Aug 4;35(31):4141-8. doi: 10.1038/onc.2015.481. Epub 2015 Dec 21. Oncogene. 2016. PMID: 26686090
Acetylation of C/EBPε is a prerequisite for terminal neutrophil differentiation.
Bartels M, Govers AM, Fleskens V, Lourenço AR, Pals CE, Vervoort SJ, van Gent R, Brenkman AB, Bierings MB, Ackerman SJ, van Loosdregt J, Coffer PJ. Bartels M, et al. Among authors: pals ce. Blood. 2015 Mar 12;125(11):1782-92. doi: 10.1182/blood-2013-12-543850. Epub 2015 Jan 7. Blood. 2015. PMID: 25568349 Free article.
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