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A mutation in the canalicular phospholipid transporter gene, ABCB4, is associated with cholestasis, ductopenia, and cirrhosis in adults.
Gotthardt D, Runz H, Keitel V, Fischer C, Flechtenmacher C, Wirtenberger M, Weiss KH, Imparato S, Braun A, Hemminki K, Stremmel W, Rüschendorf F, Stiehl A, Kubitz R, Burwinkel B, Schirmacher P, Knisely AS, Zschocke J, Sauer P. Gotthardt D, et al. Among authors: stremmel w. Hepatology. 2008 Oct;48(4):1157-66. doi: 10.1002/hep.22485. Hepatology. 2008. PMID: 18781607
S100A9 is a biliary protein marker of disease activity in primary sclerosing cholangitis.
Reinhard L, Rupp C, Riedel HD, Ruppert T, Giese T, Flechtenmacher C, Weiss KH, Kloeters-Plachky P, Stremmel W, Schirmacher P, Sauer P, Gotthardt DN. Reinhard L, et al. Among authors: stremmel w. PLoS One. 2012;7(1):e29821. doi: 10.1371/journal.pone.0029821. Epub 2012 Jan 11. PLoS One. 2012. PMID: 22253789 Free PMC article.
PNPLA3 in end-stage liver disease: alcohol consumption, hepatocellular carcinoma development, and transplantation-free survival.
Friedrich K, Wannhoff A, Kattner S, Brune M, Hov JR, Weiss KH, Antoni C, Dollinger M, Neumann-Haefelin C, Seufferlein T, Schemmer P, Schirmacher P, Stremmel W, Gotthardt DN. Friedrich K, et al. Among authors: stremmel w. J Gastroenterol Hepatol. 2014;29(7):1477-84. doi: 10.1111/jgh.12540. J Gastroenterol Hepatol. 2014. PMID: 25273282
Inflammation But Not Biliary Obstruction Is Associated With Carbohydrate Antigen 19-9 Levels in Patients With Primary Sclerosing Cholangitis.
Wannhoff A, Rupp C, Friedrich K, Brune M, Knierim J, Flechtenmacher C, Sauer P, Stremmel W, Hov JR, Schirmacher P, Weiss KH, Gotthardt DN. Wannhoff A, et al. Among authors: stremmel w. Clin Gastroenterol Hepatol. 2015 Dec;13(13):2372-9. doi: 10.1016/j.cgh.2015.07.014. Epub 2015 Jul 17. Clin Gastroenterol Hepatol. 2015. PMID: 26192140
A common genetic variant of fucosyltransferase 2 correlates with serum carcinoembryonic antigen levels and affects cancer screening in patients with primary sclerosing cholangitis.
Wannhoff A, Folseraas T, Brune M, Rupp C, Friedrich K, Knierim J, Weiss KH, Sauer P, Flechtenmacher C, Schirmacher P, Stremmel W, Hov JR, Gotthardt DN. Wannhoff A, et al. Among authors: stremmel w. United European Gastroenterol J. 2016 Feb;4(1):84-91. doi: 10.1177/2050640615581577. Epub 2015 Apr 9. United European Gastroenterol J. 2016. PMID: 26966527 Free PMC article.
CD14 is associated with biliary stricture formation.
Friedrich K, Smit M, Brune M, Giese T, Rupp C, Wannhoff A, Kloeters P, Leopold Y, Denk GU, Weiss KH, Stremmel W, Sauer P, Hohenester S, Schirmacher P, Schemmer P, Gotthardt DN. Friedrich K, et al. Among authors: stremmel w. Hepatology. 2016 Sep;64(3):843-52. doi: 10.1002/hep.28543. Epub 2016 Apr 20. Hepatology. 2016. PMID: 26970220
681 results