Jarpe M - Search Results

1

Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance.

Cook C, Carlomagno Y, Gendron TF, Dunmore J, Scheffel K, Stetler C, Davis M, Dickson D, Jarpe M, DeTure M, Petrucelli L. Cook C, et al. Among authors: jarpe m. Hum Mol Genet. 2014 Jan 1;23(1):104-16. doi: 10.1093/hmg/ddt402. Epub 2013 Aug 19. Hum Mol Genet. 2014. PMID: 23962722 Free PMC article.

2

Valproate reverses mania-like behaviors in mice via preferential targeting of HDAC2.

Logan RW, Ozburn AR, Arey RN, Ketchesin KD, Winquist A, Crain A, Tobe BTD, Becker-Krail D, Jarpe MB, Xue X, Zong W, Huo Z, Parekh PK, Zhu X, Fitzgerald E, Zhang H, Oliver-Smith J, DePoy LM, Hildebrand MA, Snyder EY, Tseng GC, McClung CA. Logan RW, et al. Among authors: jarpe mb. Mol Psychiatry. 2021 Aug;26(8):4066-4084. doi: 10.1038/s41380-020-00958-2. Epub 2020 Nov 24. Mol Psychiatry. 2021. PMID: 33235333 Free PMC article.

3

Pharmacological inhibition of HDAC6 reverses cognitive impairment and tau pathology as a result of cisplatin treatment.

Ma J, Huo X, Jarpe MB, Kavelaars A, Heijnen CJ. Ma J, et al. Among authors: jarpe mb. Acta Neuropathol Commun. 2018 Oct 1;6(1):103. doi: 10.1186/s40478-018-0604-3. Acta Neuropathol Commun. 2018. PMID: 30270813 Free PMC article.

4

Restoration of histone acetylation ameliorates disease and metabolic abnormalities in a FUS mouse model.

Rossaert E, Pollari E, Jaspers T, Van Helleputte L, Jarpe M, Van Damme P, De Bock K, Moisse M, Van Den Bosch L. Rossaert E, et al. Among authors: jarpe m. Acta Neuropathol Commun. 2019 Jul 5;7(1):107. doi: 10.1186/s40478-019-0750-2. Acta Neuropathol Commun. 2019. PMID: 31277703 Free PMC article.

5

Selective Histone Deacetylase 6 Inhibition Normalizes B Cell Activation and Germinal Center Formation in a Model of Systemic Lupus Erythematosus.

Ren J, Catalina MD, Eden K, Liao X, Read KA, Luo X, McMillan RP, Hulver MW, Jarpe M, Bachali P, Grammer AC, Lipsky PE, Reilly CM. Ren J, et al. Among authors: jarpe m. Front Immunol. 2019 Oct 25;10:2512. doi: 10.3389/fimmu.2019.02512. eCollection 2019. Front Immunol. 2019. PMID: 31708928 Free PMC article.

6

HDAC6-selective inhibitors decrease nerve-injury and inflammation-associated mechanical hypersensitivity in mice.

Sakloth F, Manouras L, Avrampou K, Mitsi V, Serafini RA, Pryce KD, Cogliani V, Berton O, Jarpe M, Zachariou V. Sakloth F, et al. Among authors: jarpe m. Psychopharmacology (Berl). 2020 Jul;237(7):2139-2149. doi: 10.1007/s00213-020-05525-9. Epub 2020 May 9. Psychopharmacology (Berl). 2020. PMID: 32388618 Free PMC article.

7

HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients.

Guo W, Naujock M, Fumagalli L, Vandoorne T, Baatsen P, Boon R, Ordovás L, Patel A, Welters M, Vanwelden T, Geens N, Tricot T, Benoy V, Steyaert J, Lefebvre-Omar C, Boesmans W, Jarpe M, Sterneckert J, Wegner F, Petri S, Bohl D, Vanden Berghe P, Robberecht W, Van Damme P, Verfaillie C, Van Den Bosch L. Guo W, et al. Among authors: jarpe m. Nat Commun. 2017 Oct 11;8(1):861. doi: 10.1038/s41467-017-00911-y. Nat Commun. 2017. PMID: 29021520 Free PMC article.

8

HDAC6 inhibition effectively reverses chemotherapy-induced peripheral neuropathy.

Krukowski K, Ma J, Golonzhka O, Laumet GO, Gutti T, van Duzer JH, Mazitschek R, Jarpe MB, Heijnen CJ, Kavelaars A. Krukowski K, et al. Pain. 2017 Jun;158(6):1126-1137. doi: 10.1097/j.pain.0000000000000893. Pain. 2017. PMID: 28267067 Free PMC article.

9

Chemical Inhibition of Histone Deacetylases 1 and 2 Induces Fetal Hemoglobin through Activation of GATA2.

Shearstone JR, Golonzhka O, Chonkar A, Tamang D, van Duzer JH, Jones SS, Jarpe MB. Shearstone JR, et al. PLoS One. 2016 Apr 13;11(4):e0153767. doi: 10.1371/journal.pone.0153767. eCollection 2016. PLoS One. 2016. PMID: 27073918 Free PMC article.

10

Selective HDAC inhibition by ACY-241 enhances the activity of paclitaxel in solid tumor models.

Huang P, Almeciga-Pinto I, Jarpe M, van Duzer JH, Mazitschek R, Yang M, Jones SS, Quayle SN. Huang P, et al. Among authors: jarpe m. Oncotarget. 2017 Jan 10;8(2):2694-2707. doi: 10.18632/oncotarget.13738. Oncotarget. 2017. PMID: 27926524 Free PMC article.

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