Nagase H - Search Results

1

Inhibition of MMP-9 using a pyrrole-imidazole polyamide reduces cell invasion in renal cell carcinoma.

Sato A, Nagase H, Obinata D, Fujiwara K, Fukuda N, Soma M, Yamaguchi K, Kawata N, Takahashi S. Sato A, et al. Among authors: nagase h. Int J Oncol. 2013 Nov;43(5):1441-6. doi: 10.3892/ijo.2013.2073. Epub 2013 Aug 21. Int J Oncol. 2013. PMID: 23969530

2

Inhibition of MMP-9 transcription and suppression of tumor metastasis by pyrrole-imidazole polyamide.

Wang X, Nagase H, Watanabe T, Nobusue H, Suzuki T, Asami Y, Shinojima Y, Kawashima H, Takagi K, Mishra R, Igarashi J, Kimura M, Takayama T, Fukuda N, Sugiyama H. Wang X, et al. Among authors: nagase h. Cancer Sci. 2010 Mar;101(3):759-66. doi: 10.1111/j.1349-7006.2009.01435.x. Epub 2009 Nov 14. Cancer Sci. 2010. PMID: 20085585 Free PMC article.

3

Pyrrole-imidazole polyamide targeted to break fusion sites in TMPRSS2 and ERG gene fusion represses prostate tumor growth.

Obinata D, Ito A, Fujiwara K, Takayama K, Ashikari D, Murata Y, Yamaguchi K, Urano T, Fujimura T, Fukuda N, Soma M, Watanabe T, Nagase H, Inoue S, Takahashi S. Obinata D, et al. Among authors: nagase h. Cancer Sci. 2014 Oct;105(10):1272-8. doi: 10.1111/cas.12493. Epub 2014 Sep 18. Cancer Sci. 2014. PMID: 25088707 Free PMC article.

4

Inhibition of human osteosarcoma cell migration and invasion by a gene silencer, pyrrole-imidazole polyamide, targeted at the human MMP9 NF-κB binding site.

Kojima T, Wang X, Fujiwara K, Osaka S, Yoshida Y, Osaka E, Taniguchi M, Ueno T, Fukuda N, Soma M, Tokuhashi Y, Nagase H. Kojima T, et al. Among authors: nagase h. Biol Pharm Bull. 2014;37(9):1460-5. doi: 10.1248/bpb.b14-00147. Biol Pharm Bull. 2014. PMID: 25177029 Free article.

5

Pyrrole-imidazole polyamide-mediated silencing of KCNQ1OT1 expression induces cell death in Wilms' tumor cells.

Yoshizawa S, Fujiwara K, Sugito K, Uekusa S, Kawashima H, Hoshi R, Watanabe Y, Hirano T, Furuya T, Masuko T, Ueno T, Fukuda N, Soma M, Ozaki T, Koshinaga T, Nagase H. Yoshizawa S, et al. Among authors: nagase h. Int J Oncol. 2015 Jul;47(1):115-21. doi: 10.3892/ijo.2015.3018. Epub 2015 May 22. Int J Oncol. 2015. PMID: 25998555

6

Effects of Pyrrole-Imidazole Polyamides Targeting Human TGF-β1 on the Malignant Phenotypes of Liver Cancer Cells.

Takagi K, Midorikawa Y, Takayama T, Abe H, Fujiwara K, Soma M, Nagase H, Miki T, Fukuda N. Takagi K, et al. Among authors: nagase h. Molecules. 2020 Jun 23;25(12):2883. doi: 10.3390/molecules25122883. Molecules. 2020. PMID: 32585841 Free PMC article.

7

Targeting Oct1 genomic function inhibits androgen receptor signaling and castration-resistant prostate cancer growth.

Obinata D, Takayama K, Fujiwara K, Suzuki T, Tsutsumi S, Fukuda N, Nagase H, Fujimura T, Urano T, Homma Y, Aburatani H, Takahashi S, Inoue S. Obinata D, et al. Among authors: nagase h. Oncogene. 2016 Dec 8;35(49):6350-6358. doi: 10.1038/onc.2016.171. Epub 2016 Jun 6. Oncogene. 2016. PMID: 27270436

8

Development of pyrrole-imidazole polyamide for specific regulation of human aurora kinase-A and -B gene expression.

Takahashi T, Asami Y, Kitamura E, Suzuki T, Wang X, Igarashi J, Morohashi A, Shinojima Y, Kanou H, Saito K, Takasu T, Nagase H, Harada Y, Kuroda K, Watanabe T, Kumamoto S, Aoyama T, Matsumoto Y, Bando T, Sugiyama H, Yoshida-Noro C, Fukuda N, Hayashi N. Takahashi T, et al. Among authors: nagase h. Chem Biol. 2008 Aug 25;15(8):829-41. doi: 10.1016/j.chembiol.2008.06.006. Chem Biol. 2008. PMID: 18721754

9

A pyrrole-imidazole polyamide targeting transforming growth factor-beta1 inhibits restenosis and preserves endothelialization in the injured artery.

Yao EH, Fukuda N, Ueno T, Matsuda H, Nagase H, Matsumoto Y, Sugiyama H, Matsumoto K. Yao EH, et al. Among authors: nagase h. Cardiovasc Res. 2009 Mar 1;81(4):797-804. doi: 10.1093/cvr/cvn355. Epub 2008 Dec 20. Cardiovasc Res. 2009. PMID: 19098300

10

A novel gene silencer, pyrrole-imidazole polyamide targeting human lectin-like oxidized low-density lipoprotein receptor-1 gene improves endothelial cell function.

Ueno T, Fukuda N, Tsunemi A, Yao EH, Matsuda H, Tahira K, Matsumoto T, Matsumoto K, Matsumoto Y, Nagase H, Sugiyama H, Sawamura T. Ueno T, et al. Among authors: nagase h. J Hypertens. 2009 Mar;27(3):508-16. doi: 10.1097/hjh.0b013e3283207fe1. J Hypertens. 2009. PMID: 19330905

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