Fukushima H - Search Results

1

SCF-mediated Cdh1 degradation defines a negative feedback system that coordinates cell-cycle progression.

Fukushima H, Ogura K, Wan L, Lu Y, Li V, Gao D, Liu P, Lau AW, Wu T, Kirschner MW, Inuzuka H, Wei W. Fukushima H, et al. Cell Rep. 2013 Aug 29;4(4):803-16. doi: 10.1016/j.celrep.2013.07.031. Epub 2013 Aug 22. Cell Rep. 2013. PMID: 23972993 Free PMC article.

2

SCF(Fbw7) modulates the NFkB signaling pathway by targeting NFkB2 for ubiquitination and destruction.

Fukushima H, Matsumoto A, Inuzuka H, Zhai B, Lau AW, Wan L, Gao D, Shaik S, Yuan M, Gygi SP, Jimi E, Asara JM, Nakayama K, Nakayama KI, Wei W. Fukushima H, et al. Cell Rep. 2012 May 31;1(5):434-43. doi: 10.1016/j.celrep.2012.04.002. Cell Rep. 2012. PMID: 22708077 Free PMC article.

3

SCF(β-TRCP) suppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2.

Shaik S, Nucera C, Inuzuka H, Gao D, Garnaas M, Frechette G, Harris L, Wan L, Fukushima H, Husain A, Nose V, Fadda G, Sadow PM, Goessling W, North T, Lawler J, Wei W. Shaik S, et al. Among authors: fukushima h. J Exp Med. 2012 Jul 2;209(7):1289-307. doi: 10.1084/jem.20112446. Epub 2012 Jun 18. J Exp Med. 2012. PMID: 22711876 Free PMC article.

4

Acetylation-dependent regulation of Skp2 function.

Inuzuka H, Gao D, Finley LW, Yang W, Wan L, Fukushima H, Chin YR, Zhai B, Shaik S, Lau AW, Wang Z, Gygi SP, Nakayama K, Teruya-Feldstein J, Toker A, Haigis MC, Pandolfi PP, Wei W. Inuzuka H, et al. Among authors: fukushima h. Cell. 2012 Jul 6;150(1):179-93. doi: 10.1016/j.cell.2012.05.038. Cell. 2012. PMID: 22770219 Free PMC article.

5

DNA damage-induced activation of ATM promotes β-TRCP-mediated Mdm2 ubiquitination and destruction.

Wang Z, Inuzuka H, Zhong J, Fukushima H, Wan L, Liu P, Wei W. Wang Z, et al. Among authors: fukushima h. Oncotarget. 2012 Sep;3(9):1026-35. doi: 10.18632/oncotarget.640. Oncotarget. 2012. PMID: 22976441 Free PMC article.

6

Regulation of APC(Cdh1) E3 ligase activity by the Fbw7/cyclin E signaling axis contributes to the tumor suppressor function of Fbw7.

Lau AW, Inuzuka H, Fukushima H, Wan L, Liu P, Gao D, Sun Y, Wei W. Lau AW, et al. Among authors: fukushima h. Cell Res. 2013 Jul;23(7):947-61. doi: 10.1038/cr.2013.67. Epub 2013 May 14. Cell Res. 2013. PMID: 23670162 Free PMC article.

7

SCFβ-TRCP regulates osteoclastogenesis via promoting CYLD ubiquitination.

Wu X, Fukushima H, North BJ, Nagaoka Y, Nagashima K, Deng F, Okabe K, Inuzuka H, Wei W. Wu X, et al. Among authors: fukushima h. Oncotarget. 2014 Jun 30;5(12):4211-21. doi: 10.18632/oncotarget.1971. Oncotarget. 2014. PMID: 24961988 Free PMC article.

8

Novel insights into the molecular mechanisms governing Mdm2 ubiquitination and destruction.

Inuzuka H, Fukushima H, Shaik S, Wei W. Inuzuka H, et al. Among authors: fukushima h. Oncotarget. 2010 Nov;1(7):685-690. doi: 10.18632/oncotarget.202. Oncotarget. 2010. PMID: 21317463 Free PMC article. Review.

9

Mcl-1 ubiquitination and destruction.

Inuzuka H, Fukushima H, Shaik S, Liu P, Lau AW, Wei W. Inuzuka H, et al. Among authors: fukushima h. Oncotarget. 2011 Mar;2(3):239-44. doi: 10.18632/oncotarget.242. Oncotarget. 2011. PMID: 21608150 Free PMC article. Review.

10

mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.

Gao D, Inuzuka H, Tan MK, Fukushima H, Locasale JW, Liu P, Wan L, Zhai B, Chin YR, Shaik S, Lyssiotis CA, Gygi SP, Toker A, Cantley LC, Asara JM, Harper JW, Wei W. Gao D, et al. Among authors: fukushima h. Mol Cell. 2011 Oct 21;44(2):290-303. doi: 10.1016/j.molcel.2011.08.030. Mol Cell. 2011. PMID: 22017875 Free PMC article.

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