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Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Brown NG, VanderLinden R, Watson ER, Weissmann F, Ordureau A, Wu KP, Zhang W, Yu S, Mercredi PY, Harrison JS, Davidson IF, Qiao R, Lu Y, Dube P, Brunner MR, Grace CRR, Miller DJ, Haselbach D, Jarvis MA, Yamaguchi M, Yanishevski D, Petzold G, Sidhu SS, Kuhlman B, Kirschner MW, Harper JW, Peters JM, Stark H, Schulman BA. Brown NG, et al. Among authors: lu y. Cell. 2016 Jun 2;165(6):1440-1453. doi: 10.1016/j.cell.2016.05.037. Cell. 2016. PMID: 27259151 Free PMC article.
Structural basis for dynamic regulation of the human 26S proteasome.
Chen S, Wu J, Lu Y, Ma YB, Lee BH, Yu Z, Ouyang Q, Finley DJ, Kirschner MW, Mao Y. Chen S, et al. Among authors: lu y. Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):12991-12996. doi: 10.1073/pnas.1614614113. Epub 2016 Oct 21. Proc Natl Acad Sci U S A. 2016. PMID: 27791164 Free PMC article.
The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function.
Wan L, Chen M, Cao J, Dai X, Yin Q, Zhang J, Song SJ, Lu Y, Liu J, Inuzuka H, Katon JM, Berry K, Fung J, Ng C, Liu P, Song MS, Xue L, Bronson RT, Kirschner MW, Cui R, Pandolfi PP, Wei W. Wan L, et al. Among authors: lu y. Cancer Discov. 2017 Apr;7(4):424-441. doi: 10.1158/2159-8290.CD-16-0647. Epub 2017 Feb 7. Cancer Discov. 2017. PMID: 28174173 Free PMC article.
Molecular mechanism for activation of the 26S proteasome by ZFAND5.
Lee D, Zhu Y, Colson L, Wang X, Chen S, Tkacik E, Huang L, Ouyang Q, Goldberg AL, Lu Y. Lee D, et al. Among authors: lu y. Mol Cell. 2023 Aug 17;83(16):2959-2975.e7. doi: 10.1016/j.molcel.2023.07.023. Mol Cell. 2023. PMID: 37595557 Free PMC article.
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