Mladenov R - Search Results

1

Granzyme M as a novel effector molecule for human cytolytic fusion proteins: CD64-specific cytotoxicity of Gm-H22(scFv) against leukemic cells.

Schiffer S, Letzian S, Jost E, Mladenov R, Hristodorov D, Huhn M, Fischer R, Barth S, Thepen T. Schiffer S, et al. Among authors: mladenov r. Cancer Lett. 2013 Dec 1;341(2):178-85. doi: 10.1016/j.canlet.2013.08.005. Epub 2013 Aug 22. Cancer Lett. 2013. PMID: 23973499

2

Microtubule-associated protein tau facilitates the targeted killing of proliferating cancer cells in vitro and in a xenograft mouse tumour model in vivo.

Hristodorov D, Mladenov R, Pardo A, Pham AT, Huhn M, Fischer R, Thepen T, Barth S. Hristodorov D, et al. Among authors: mladenov r. Br J Cancer. 2013 Sep 17;109(6):1570-8. doi: 10.1038/bjc.2013.457. Epub 2013 Aug 13. Br J Cancer. 2013. PMID: 23942071 Free PMC article.

3

Macrophage-targeted therapy: CD64-based immunotoxins for treatment of chronic inflammatory diseases.

Hristodorov D, Mladenov R, Huhn M, Barth S, Thepen T. Hristodorov D, et al. Among authors: mladenov r. Toxins (Basel). 2012 Sep;4(9):676-94. doi: 10.3390/toxins4090676. Epub 2012 Sep 14. Toxins (Basel). 2012. PMID: 23105975 Free PMC article. Review.

4

Human microtubule-associated protein tau mediates targeted killing of CD30(+) lymphoma cells in vitro and inhibits tumour growth in vivo.

Hristodorov D, Nordlohne J, Mladenov R, Huhn M, Fischer R, Thepen T, Barth S. Hristodorov D, et al. Among authors: mladenov r. Br J Haematol. 2014 Jan;164(2):251-7. doi: 10.1111/bjh.12626. Epub 2013 Oct 25. Br J Haematol. 2014. PMID: 24164493 Free article.

5

EpCAM-selective elimination of carcinoma cells by a novel MAP-based cytolytic fusion protein.

Hristodorov D, Amoury M, Mladenov R, Niesen J, Arens K, Berges N, Hein L, Di Fiore S, Pham AT, Huhn M, Helfrich W, Fischer R, Thepen T, Barth S. Hristodorov D, et al. Among authors: mladenov r. Mol Cancer Ther. 2014 Sep;13(9):2194-202. doi: 10.1158/1535-7163.MCT-13-0781. Epub 2014 Jun 30. Mol Cancer Ther. 2014. PMID: 24980949

6

A CSPG4-specific immunotoxin kills rhabdomyosarcoma cells and binds to primary tumor tissues.

Brehm H, Niesen J, Mladenov R, Stein C, Pardo A, Fey G, Helfrich W, Fischer R, Gattenlöhner S, Barth S. Brehm H, et al. Among authors: mladenov r. Cancer Lett. 2014 Oct 1;352(2):228-35. doi: 10.1016/j.canlet.2014.07.006. Epub 2014 Jul 10. Cancer Lett. 2014. PMID: 25016058

7

Recombinant H22(scFv) blocks CD64 and prevents the capture of anti-TNF monoclonal antibody. A potential strategy to enhance anti-TNF therapy.

Hristodorov D, Mladenov R, Brehm H, Fischer R, Barth S, Thepen T. Hristodorov D, et al. Among authors: mladenov r. MAbs. 2014;6(5):1283-9. doi: 10.4161/mabs.32182. MAbs. 2014. PMID: 25517313 Free PMC article.

8

Targeted killing of rhabdomyosarcoma cells by a MAP-based human cytolytic fusion protein.

Brehm H, Hristodorov D, Pardo A, Mladenov R, Niesen J, Fischer R, Tur MK, Barth S. Brehm H, et al. Among authors: mladenov r. Cancer Lett. 2015 Sep 1;365(2):149-55. doi: 10.1016/j.canlet.2015.04.004. Epub 2015 Apr 14. Cancer Lett. 2015. PMID: 25888452

9

The Fc-alpha receptor is a new target antigen for immunotherapy of myeloid leukemia.

Mladenov R, Hristodorov D, Cremer C, Hein L, Kreutzer F, Stroisch T, Niesen J, Brehm H, Blume T, Brümmendorf TH, Jost E, Thepen T, Fischer R, Stockmeyer B, Barth S, Stein C. Mladenov R, et al. Int J Cancer. 2015 Dec 1;137(11):2729-38. doi: 10.1002/ijc.29628. Epub 2015 Jun 12. Int J Cancer. 2015. PMID: 26041304

10

Targeting CD64 mediates elimination of M1 but not M2 macrophages in vitro and in cutaneous inflammation in mice and patient biopsies.

Hristodorov D, Mladenov R, von Felbert V, Huhn M, Fischer R, Barth S, Thepen T. Hristodorov D, et al. Among authors: mladenov r. MAbs. 2015;7(5):853-62. doi: 10.1080/19420862.2015.1066950. MAbs. 2015. PMID: 26218624 Free PMC article.

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