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Page 1
The duration of sleep promoting efficacy by dual orexin receptor antagonists is dependent upon receptor occupancy threshold.
Gotter AL, Winrow CJ, Brunner J, Garson SL, Fox SV, Binns J, Harrell CM, Cui D, Yee KL, Stiteler M, Stevens J, Savitz A, Tannenbaum PL, Tye SJ, McDonald T, Yao L, Kuduk SD, Uslaner J, Coleman PJ, Renger JJ. Gotter AL, et al. Among authors: binns j. BMC Neurosci. 2013 Aug 28;14:90. doi: 10.1186/1471-2202-14-90. BMC Neurosci. 2013. PMID: 23981345 Free PMC article.
Orexin receptor antagonists differ from standard sleep drugs by promoting sleep at doses that do not disrupt cognition.
Uslaner JM, Tye SJ, Eddins DM, Wang X, Fox SV, Savitz AT, Binns J, Cannon CE, Garson SL, Yao L, Hodgson R, Stevens J, Bowlby MR, Tannenbaum PL, Brunner J, Mcdonald TP, Gotter AL, Kuduk SD, Coleman PJ, Winrow CJ, Renger JJ. Uslaner JM, et al. Among authors: binns j. Sci Transl Med. 2013 Apr 3;5(179):179ra44. doi: 10.1126/scitranslmed.3005213. Sci Transl Med. 2013. PMID: 23552372
Orexin receptor antagonist-induced sleep does not impair the ability to wake in response to emotionally salient acoustic stimuli in dogs.
Tannenbaum PL, Stevens J, Binns J, Savitz AT, Garson SL, Fox SV, Coleman P, Kuduk SD, Gotter AL, Marino M, Tye SJ, Uslaner JM, Winrow CJ, Renger JJ. Tannenbaum PL, et al. Among authors: binns j. Front Behav Neurosci. 2014 May 16;8:182. doi: 10.3389/fnbeh.2014.00182. eCollection 2014. Front Behav Neurosci. 2014. PMID: 24904334 Free PMC article.
Discovery of a pharmacologically active antagonist of the two-pore-domain potassium channel K2P9.1 (TASK-3).
Coburn CA, Luo Y, Cui M, Wang J, Soll R, Dong J, Hu B, Lyon MA, Santarelli VP, Kraus RL, Gregan Y, Wang Y, Fox SV, Binns J, Doran SM, Reiss DR, Tannenbaum PL, Gotter AL, Meinke PT, Renger JJ. Coburn CA, et al. Among authors: binns j. ChemMedChem. 2012 Jan 2;7(1):123-33. doi: 10.1002/cmdc.201100351. Epub 2011 Sep 14. ChemMedChem. 2012. PMID: 21916012
Pharmacological validation of candidate causal sleep genes identified in an N2 cross.
Brunner JI, Gotter AL, Millstein J, Garson S, Binns J, Fox SV, Savitz AT, Yang HS, Fitzpatrick K, Zhou L, Owens JR, Webber AL, Vitaterna MH, Kasarskis A, Uebele VN, Turek F, Renger JJ, Winrow CJ. Brunner JI, et al. Among authors: binns j. J Neurogenet. 2011 Dec;25(4):167-81. doi: 10.3109/01677063.2011.628426. J Neurogenet. 2011. PMID: 22091728 Free PMC article.
Age and sex-related variations in murine laryngeal microbiota.
An R, Venkatraman A, Binns J, Saric C, Rey FE, Thibeault SL. An R, et al. Among authors: binns j. PLoS One. 2024 May 14;19(5):e0300672. doi: 10.1371/journal.pone.0300672. eCollection 2024. PLoS One. 2024. PMID: 38743725 Free PMC article.
93 results