Freeman AK - Search Results

1

The importance of Raf dimerization in cell signaling.

Freeman AK, Ritt DA, Morrison DK. Freeman AK, et al. Small GTPases. 2013 Jul-Sep;4(3):180-5. doi: 10.4161/sgtp.26117. Epub 2013 Aug 28. Small GTPases. 2013. PMID: 23985533 Free PMC article.

2

Complexity in KSR function revealed by Raf inhibitor and KSR structure studies.

McKay MM, Freeman AK, Morrison DK. McKay MM, et al. Among authors: freeman ak. Small GTPases. 2011 Sep;2(5):276-281. doi: 10.4161/sgtp.2.5.17740. Epub 2011 Sep 1. Small GTPases. 2011. PMID: 22292131 Free PMC article.

3

Effects of Raf dimerization and its inhibition on normal and disease-associated Raf signaling.

Freeman AK, Ritt DA, Morrison DK. Freeman AK, et al. Mol Cell. 2013 Feb 21;49(4):751-8. doi: 10.1016/j.molcel.2012.12.018. Epub 2013 Jan 24. Mol Cell. 2013. PMID: 23352452 Free PMC article.

4

14-3-3 Proteins: diverse functions in cell proliferation and cancer progression.

Freeman AK, Morrison DK. Freeman AK, et al. Semin Cell Dev Biol. 2011 Sep;22(7):681-7. doi: 10.1016/j.semcdb.2011.08.009. Epub 2011 Aug 22. Semin Cell Dev Biol. 2011. PMID: 21884813 Free PMC article. Review.

5

Hyperactivation of MAPK Signaling Is Deleterious to RAS/RAF-mutant Melanoma.

Leung GP, Feng T, Sigoillot FD, Geyer FC, Shirley MD, Ruddy DA, Rakiec DP, Freeman AK, Engelman JA, Jaskelioff M, Stuart DD. Leung GP, et al. Among authors: freeman ak. Mol Cancer Res. 2019 Jan;17(1):199-211. doi: 10.1158/1541-7786.MCR-18-0327. Epub 2018 Sep 10. Mol Cancer Res. 2019. PMID: 30201825

6

RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation.

Crowe MS, Zavorotinskaya T, Voliva CF, Shirley MD, Wang Y, Ruddy DA, Rakiec DP, Engelman JA, Stuart DD, Freeman AK. Crowe MS, et al. Among authors: freeman ak. Mol Cancer Res. 2021 Jun;19(6):1063-1075. doi: 10.1158/1541-7786.MCR-20-1022. Epub 2021 Mar 11. Mol Cancer Res. 2021. PMID: 33707308

7

BRAF-inhibitor Associated MEK Mutations Increase RAF-Dependent and -Independent Enzymatic Activity.

Emery CM, Monaco KA, Wang P, Balak M, Freeman A, Meltzer J, Delach SM, Rakiec D, Ruddy DA, Korn JM, Haling J, Acker MG, Caponigro G. Emery CM, et al. Mol Cancer Res. 2017 Oct;15(10):1431-1444. doi: 10.1158/1541-7786.MCR-17-0211. Epub 2017 Jun 27. Mol Cancer Res. 2017. PMID: 28655712

8

Developmental genes controlling neural circuit formation are expressed in the early postnatal hypothalamus and cellular lining of the third ventricle.

Freeman AK, Glendining KA, Jasoni CL. Freeman AK, et al. J Neuroendocrinol. 2021 Sep;33(9):e13020. doi: 10.1111/jne.13020. Epub 2021 Aug 23. J Neuroendocrinol. 2021. PMID: 34423876

9

Can a Silver-Coated Arthrodesis Implant Provide a Viable Alternative to Above Knee Amputation in the Unsalvageable, Infected Total Knee Arthroplasty?

Wilding CP, Cooper GA, Freeman AK, Parry MC, Jeys L. Wilding CP, et al. Among authors: freeman ak. J Arthroplasty. 2016 Nov;31(11):2542-2547. doi: 10.1016/j.arth.2016.04.009. Epub 2016 Apr 22. J Arthroplasty. 2016. PMID: 27181490

10

Hypotensive Epidural Anesthesia Reduces Blood Loss in Pelvic and Sacral Bone Tumor Resections.

Freeman AK, Thorne CJ, Gaston CL, Shellard R, Neal T, Parry MC, Grimer RJ, Jeys L. Freeman AK, et al. Clin Orthop Relat Res. 2017 Mar;475(3):634-640. doi: 10.1007/s11999-016-4858-4. Epub 2016 May 12. Clin Orthop Relat Res. 2017. PMID: 27172818 Free PMC article.

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