Pommier Y - Search Results

1

Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of noncamptothecin topoisomerase I (Top1) inhibitors.

Taliani S, Pugliesi I, Barresi E, Salerno S, Marchand C, Agama K, Simorini F, La Motta C, Marini AM, Di Leva FS, Marinelli L, Cosconati S, Novellino E, Pommier Y, Di Santo R, Da Settimo F. Taliani S, et al. Among authors: pommier y. J Med Chem. 2013 Sep 26;56(18):7458-62. doi: 10.1021/jm400932c. Epub 2013 Sep 16. J Med Chem. 2013. PMID: 23987476 Free PMC article.

2

Synthesis of cytotoxic indenoisoquinoline topoisomerase I poisons.

Strumberg D, Pommier Y, Paull K, Jayaraman M, Nagafuji P, Cushman M. Strumberg D, et al. Among authors: pommier y. J Med Chem. 1999 Feb 11;42(3):446-57. doi: 10.1021/jm9803323. J Med Chem. 1999. PMID: 9986716

3

Retroviral integrase inhibitors year 2000: update and perspectives.

Pommier Y, Marchand C, Neamati N. Pommier Y, et al. Antiviral Res. 2000 Sep;47(3):139-48. doi: 10.1016/s0166-3542(00)00112-1. Antiviral Res. 2000. PMID: 10974366 Review.

4

Synthesis of new indeno[1,2-c]isoquinolines: cytotoxic non-camptothecin topoisomerase I inhibitors.

Cushman M, Jayaraman M, Vroman JA, Fukunaga AK, Fox BM, Kohlhagen G, Strumberg D, Pommier Y. Cushman M, et al. Among authors: pommier y. J Med Chem. 2000 Oct 5;43(20):3688-98. doi: 10.1021/jm000029d. J Med Chem. 2000. PMID: 11020283

5

Synthesis of new dihydroindeno[1,2-c]isoquinoline and indenoisoquinolinium chloride topoisomerase I inhibitors having high in vivo anticancer activity in the hollow fiber animal model.

Jayaraman M, Fox BM, Hollingshead M, Kohlhagen G, Pommier Y, Cushman M. Jayaraman M, et al. Among authors: pommier y. J Med Chem. 2002 Jan 3;45(1):242-9. doi: 10.1021/jm000498f. J Med Chem. 2002. PMID: 11754595

6

Interaction of human nuclear topoisomerase I with guanosine quartet-forming and guanosine-rich single-stranded DNA and RNA oligonucleotides.

Marchand C, Pourquier P, Laco GS, Jing N, Pommier Y. Marchand C, et al. Among authors: pommier y. J Biol Chem. 2002 Mar 15;277(11):8906-11. doi: 10.1074/jbc.M106372200. Epub 2001 Dec 26. J Biol Chem. 2002. PMID: 11756434 Free article.

7

Structural determinants for HIV-1 integrase inhibition by beta-diketo acids.

Marchand C, Zhang X, Pais GC, Cowansage K, Neamati N, Burke TR Jr, Pommier Y. Marchand C, et al. Among authors: pommier y. J Biol Chem. 2002 Apr 12;277(15):12596-603. doi: 10.1074/jbc.M110758200. Epub 2002 Jan 22. J Biol Chem. 2002. PMID: 11805103 Free article.

8

Structure activity of 3-aryl-1,3-diketo-containing compounds as HIV-1 integrase inhibitors.

Pais GC, Zhang X, Marchand C, Neamati N, Cowansage K, Svarovskaia ES, Pathak VK, Tang Y, Nicklaus M, Pommier Y, Burke TR Jr. Pais GC, et al. Among authors: pommier y. J Med Chem. 2002 Jul 18;45(15):3184-94. doi: 10.1021/jm020037p. J Med Chem. 2002. PMID: 12109903

9

Non-camptothecin DNA topoisomerase I inhibitors in cancer therapy.

Meng LH, Liao ZY, Pommier Y. Meng LH, et al. Among authors: pommier y. Curr Top Med Chem. 2003;3(3):305-20. doi: 10.2174/1568026033452546. Curr Top Med Chem. 2003. PMID: 12570765 Review.

10

Azido-containing aryl beta-diketo acid HIV-1 integrase inhibitors.

Zhang X, Pais GC, Svarovskaia ES, Marchand C, Johnson AA, Karki RG, Nicklaus MC, Pathak VK, Pommier Y, Burke TR. Zhang X, et al. Among authors: pommier y. Bioorg Med Chem Lett. 2003 Mar 24;13(6):1215-9. doi: 10.1016/s0960-894x(03)00059-3. Bioorg Med Chem Lett. 2003. PMID: 12643946

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