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The TACI receptor regulates T-cell-independent marginal zone B cell responses through innate activation-induced cell death.
Figgett WA, Fairfax K, Vincent FB, Le Page MA, Katik I, Deliyanti D, Quah PS, Verma P, Grumont R, Gerondakis S, Hertzog P, O'Reilly LA, Strasser A, Mackay F. Figgett WA, et al. Among authors: fairfax k. Immunity. 2013 Sep 19;39(3):573-83. doi: 10.1016/j.immuni.2013.05.019. Epub 2013 Sep 5. Immunity. 2013. PMID: 24012421 Free article.
BAFF-driven autoimmunity requires CD19 expression.
Fairfax KA, Tsantikos E, Figgett WA, Vincent FB, Quah PS, LePage M, Hibbs ML, Mackay F. Fairfax KA, et al. J Autoimmun. 2015 Aug;62:1-10. doi: 10.1016/j.jaut.2015.06.001. Epub 2015 Jun 20. J Autoimmun. 2015. PMID: 26103922
IL-10 regulates Aicda expression through miR-155.
Fairfax KA, Gantier MP, Mackay F, Williams BR, McCoy CE. Fairfax KA, et al. J Leukoc Biol. 2015 Jan;97(1):71-8. doi: 10.1189/jlb.2A0314-178R. Epub 2014 Nov 7. J Leukoc Biol. 2015. PMID: 25381386
NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells.
de Valle E, Grigoriadis G, O'Reilly LA, Willis SN, Maxwell MJ, Corcoran LM, Tsantikos E, Cornish JK, Fairfax KA, Vasanthakumar A, Febbraio MA, Hibbs ML, Pellegrini M, Banerjee A, Hodgkin PD, Kallies A, Mackay F, Strasser A, Gerondakis S, Gugasyan R. de Valle E, et al. Among authors: fairfax ka. J Exp Med. 2016 Apr 4;213(4):621-41. doi: 10.1084/jem.20151182. Epub 2016 Mar 28. J Exp Med. 2016. PMID: 27022143 Free PMC article.
Mcl-1 is essential for the survival of plasma cells.
Peperzak V, Vikström I, Walker J, Glaser SP, LePage M, Coquery CM, Erickson LD, Fairfax K, Mackay F, Strasser A, Nutt SL, Tarlinton DM. Peperzak V, et al. Among authors: fairfax k. Nat Immunol. 2013 Mar;14(3):290-7. doi: 10.1038/ni.2527. Epub 2013 Feb 3. Nat Immunol. 2013. PMID: 23377201 Free PMC article.
66 results