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Page 1
Structure, folding dynamics, and amyloidogenesis of D76N β2-microglobulin: roles of shear flow, hydrophobic surfaces, and α-crystallin.
Mangione PP, Esposito G, Relini A, Raimondi S, Porcari R, Giorgetti S, Corazza A, Fogolari F, Penco A, Goto Y, Lee YH, Yagi H, Cecconi C, Naqvi MM, Gillmore JD, Hawkins PN, Chiti F, Rolandi R, Taylor GW, Pepys MB, Stoppini M, Bellotti V. Mangione PP, et al. Among authors: penco a. J Biol Chem. 2013 Oct 25;288(43):30917-30. doi: 10.1074/jbc.M113.498857. Epub 2013 Sep 6. J Biol Chem. 2013. PMID: 24014031 Free PMC article.
The H50Q mutation induces a 10-fold decrease in the solubility of α-synuclein.
Porcari R, Proukakis C, Waudby CA, Bolognesi B, Mangione PP, Paton JF, Mullin S, Cabrita LD, Penco A, Relini A, Verona G, Vendruscolo M, Stoppini M, Tartaglia GG, Camilloni C, Christodoulou J, Schapira AH, Bellotti V. Porcari R, et al. Among authors: penco a. J Biol Chem. 2015 Jan 23;290(4):2395-404. doi: 10.1074/jbc.M114.610527. Epub 2014 Dec 10. J Biol Chem. 2015. PMID: 25505181 Free PMC article.
Biochemical and Electrophysiological Modification of Amyloid Transthyretin on Cardiomyocytes.
Sartiani L, Bucciantini M, Spinelli V, Leri M, Natalello A, Nosi D, Maria Doglia S, Relini A, Penco A, Giorgetti S, Gerace E, Mannaioni G, Bellotti V, Rigacci S, Cerbai E, Stefani M. Sartiani L, et al. Among authors: penco a. Biophys J. 2016 Nov 1;111(9):2024-2038. doi: 10.1016/j.bpj.2016.09.010. Biophys J. 2016. PMID: 27806283 Free PMC article.
Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers.
Mannini B, Cascella R, Zampagni M, van Waarde-Verhagen M, Meehan S, Roodveldt C, Campioni S, Boninsegna M, Penco A, Relini A, Kampinga HH, Dobson CM, Wilson MR, Cecchi C, Chiti F. Mannini B, et al. Among authors: penco a. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12479-84. doi: 10.1073/pnas.1117799109. Epub 2012 Jul 16. Proc Natl Acad Sci U S A. 2012. PMID: 22802614 Free PMC article.
28 results