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Mitochondrial redox plays a critical role in the paradoxical effects of NAPDH oxidase-derived ROS on coronary endothelium.
Shafique E, Torina A, Reichert K, Colantuono B, Nur N, Zeeshan K, Ravichandran V, Liu Y, Feng J, Zeeshan K, Benjamin LE, Irani K, Harrington EO, Sellke FW, Abid MR. Shafique E, et al. Among authors: benjamin le. Cardiovasc Res. 2017 Feb;113(2):234-246. doi: 10.1093/cvr/cvw249. Epub 2017 Jan 14. Cardiovasc Res. 2017. PMID: 28088753 Free PMC article.
Endothelial PGC-1α mediates vascular dysfunction in diabetes.
Sawada N, Jiang A, Takizawa F, Safdar A, Manika A, Tesmenitsky Y, Kang KT, Bischoff J, Kalwa H, Sartoretto JL, Kamei Y, Benjamin LE, Watada H, Ogawa Y, Higashikuni Y, Kessinger CW, Jaffer FA, Michel T, Sata M, Croce K, Tanaka R, Arany Z. Sawada N, et al. Among authors: benjamin le. Cell Metab. 2014 Feb 4;19(2):246-58. doi: 10.1016/j.cmet.2013.12.014. Cell Metab. 2014. PMID: 24506866 Free PMC article.
Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin.
Phung TL, Ziv K, Dabydeen D, Eyiah-Mensah G, Riveros M, Perruzzi C, Sun J, Monahan-Earley RA, Shiojima I, Nagy JA, Lin MI, Walsh K, Dvorak AM, Briscoe DM, Neeman M, Sessa WC, Dvorak HF, Benjamin LE. Phung TL, et al. Among authors: benjamin le. Cancer Cell. 2006 Aug;10(2):159-70. doi: 10.1016/j.ccr.2006.07.003. Cancer Cell. 2006. PMID: 16904613 Free PMC article.
RhoB differentially controls Akt function in tumor cells and stromal endothelial cells during breast tumorigenesis.
Kazerounian S, Gerald D, Huang M, Chin YR, Udayakumar D, Zheng N, O'Donnell RK, Perruzzi C, Mangiante L, Pourat J, Phung TL, Bravo-Nuevo A, Shechter S, McNamara S, Duhadaway JB, Kocher ON, Brown LF, Toker A, Prendergast GC, Benjamin LE. Kazerounian S, et al. Among authors: benjamin le. Cancer Res. 2013 Jan 1;73(1):50-61. doi: 10.1158/0008-5472.CAN-11-3055. Epub 2012 Nov 7. Cancer Res. 2013. PMID: 23135917 Free PMC article.
85 results