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84 results

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Page 1
Synthesis and biological evaluation of N-(2-fluorophenyl)-2β-deoxyfuconojirimycin acetamide as a potent inhibitor for α-l-fucosidases.
Kato A, Okaki T, Ifuku S, Sato K, Hirokami Y, Iwaki R, Kamori A, Nakagawa S, Adachi I, Kiria PG, Onomura O, Minato D, Sugimoto K, Matsuya Y, Toyooka N. Kato A, et al. Among authors: iwaki r. Bioorg Med Chem. 2013 Nov 1;21(21):6565-73. doi: 10.1016/j.bmc.2013.08.028. Epub 2013 Aug 24. Bioorg Med Chem. 2013. PMID: 24026016
N- and C-alkylation of seven-membered iminosugars generates potent glucocerebrosidase inhibitors and F508del-CFTR correctors.
Désiré J, Mondon M, Fontelle N, Nakagawa S, Hirokami Y, Adachi I, Iwaki R, Fleet GW, Alonzi DS, Twigg G, Butters TD, Bertrand J, Cendret V, Becq F, Norez C, Marrot J, Kato A, Blériot Y. Désiré J, et al. Among authors: iwaki r. Org Biomol Chem. 2014 Nov 28;12(44):8977-96. doi: 10.1039/c4ob00325j. Org Biomol Chem. 2014. PMID: 25277226
Iminosugars Inhibit Dengue Virus Production via Inhibition of ER Alpha-Glucosidases--Not Glycolipid Processing Enzymes.
Sayce AC, Alonzi DS, Killingbeck SS, Tyrrell BE, Hill ML, Caputo AT, Iwaki R, Kinami K, Ide D, Kiappes JL, Beatty PR, Kato A, Harris E, Dwek RA, Miller JL, Zitzmann N. Sayce AC, et al. Among authors: iwaki r. PLoS Negl Trop Dis. 2016 Mar 14;10(3):e0004524. doi: 10.1371/journal.pntd.0004524. eCollection 2016 Mar. PLoS Negl Trop Dis. 2016. PMID: 26974655 Free PMC article.
Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4.
Warfield KL, Plummer EM, Sayce AC, Alonzi DS, Tang W, Tyrrell BE, Hill ML, Caputo AT, Killingbeck SS, Beatty PR, Harris E, Iwaki R, Kinami K, Ide D, Kiappes JL, Kato A, Buck MD, King K, Eddy W, Khaliq M, Sampath A, Treston AM, Dwek RA, Enterlein SG, Miller JL, Zitzmann N, Ramstedt U, Shresta S. Warfield KL, et al. Among authors: iwaki r. Antiviral Res. 2016 May;129:93-98. doi: 10.1016/j.antiviral.2016.03.001. Epub 2016 Mar 3. Antiviral Res. 2016. PMID: 26946111 Free PMC article.
[Synthesis of protoberberine derivatives as ypotensives. 3. Synthesis of 10-acyloxy-5,6,13,13a-tetrahydro-2,3,11-trimethoxy-8H-dibenzo)a,g)-quinolizine (studies on the syntheses of heterocyclic compounds. DXXX) (author's transl)].
Kametani T, Nyu K, Ikeda S, Tominaga T, Iwaki R. Kametani T, et al. Among authors: iwaki r. Yakugaku Zasshi. 1973 Sep;93(9):1116-9. doi: 10.1248/yakushi1947.93.9_1116. Yakugaku Zasshi. 1973. PMID: 4797565 Japanese. No abstract available.
84 results