Naesens L - Search Results

1

Evaluation of novel acyclic nucleoside phosphonates against human and animal gammaherpesviruses revealed an altered metabolism of cyclic prodrugs upon Epstein-Barr virus reactivation in P3HR-1 cells.

Coen N, Duraffour S, Naesens L, Krecmerová M, Van den Oord J, Snoeck R, Andrei G. Coen N, et al. Among authors: naesens l. J Virol. 2013 Nov;87(22):12422-32. doi: 10.1128/JVI.02231-13. Epub 2013 Sep 11. J Virol. 2013. PMID: 24027315 Free PMC article.

2

Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine for the treatment of murine cytomegalovirus infection in severe combined immunodeficiency mice.

Neyts J, Balzarini J, Naesens L, De Clercq E. Neyts J, et al. Among authors: naesens l. J Med Virol. 1992 May;37(1):67-71. doi: 10.1002/jmv.1890370112. J Med Virol. 1992. PMID: 1320099

3

Acyclic adenine nucleoside phosphonates in plasma determined by high-performance liquid chromatography with fluorescence detection.

Naesens L, Balzarini J, De Clercq E. Naesens L, et al. Clin Chem. 1992 Apr;38(4):480-5. Clin Chem. 1992. PMID: 1568310

4

Efficacy of oral 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine (PMEDAP) in the treatment of retrovirus and cytomegalovirus infections in mice.

Naesens L, Neyts J, Balzarini J, Holy A, Rosenberg I, De Clercq E. Naesens L, et al. J Med Virol. 1993 Feb;39(2):167-72. doi: 10.1002/jmv.1890390215. J Med Virol. 1993. PMID: 8387573

5

Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine.

Balzarini J, Holy A, Jindrich J, Naesens L, Snoeck R, Schols D, De Clercq E. Balzarini J, et al. Among authors: naesens l. Antimicrob Agents Chemother. 1993 Feb;37(2):332-8. doi: 10.1128/AAC.37.2.332. Antimicrob Agents Chemother. 1993. PMID: 8452366 Free PMC article.

6

Antiviral activity of selected acyclic nucleoside analogues against human herpesvirus 6.

Reymen D, Naesens L, Balzarini J, Holý A, Dvoráková H, De Clercq E. Reymen D, et al. Among authors: naesens l. Antiviral Res. 1995 Dec;28(4):343-57. doi: 10.1016/0166-3542(95)00058-5. Antiviral Res. 1995. PMID: 8669893

7

The potential of acyclic nucleoside phosphonates as broad-spectrum antiviral agents.

Naesens L, Balzarini J, De Clercq E. Naesens L, et al. Postepy Biochem. 1995;41(5 Suppl):347-51. Postepy Biochem. 1995. PMID: 8797236 Review. No abstract available.

8

Treatment of severe laryngeal papillomatosis with intralesional injections of cidofovir [(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine].

Snoeck R, Wellens W, Desloovere C, Van Ranst M, Naesens L, De Clercq E, Feenstra L. Snoeck R, et al. Among authors: naesens l. J Med Virol. 1998 Mar;54(3):219-25. doi: 10.1002/(sici)1096-9071(199803)54:3<219::aid-jmv13>3.0.co;2-c. J Med Virol. 1998. PMID: 9515772

9

Selection and characterisation of murine leukaemia L1210 cells with high-level resistance to the cytostatic activity of the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxyethyl) adenine (PMEA).

Balzarini J, Hatse S, Naesens L, De Clercq E. Balzarini J, et al. Among authors: naesens l. Biochim Biophys Acta. 1998 Mar 12;1402(1):29-38. doi: 10.1016/s0167-4889(97)00143-2. Biochim Biophys Acta. 1998. PMID: 9551083 Free article.

10

Antitumor potential of acyclic nucleoside phosphonates.

De Clercq E, Andrei G, Balzarini J, Hatse S, Liekens S, Naesens L, Neyts J, Snoeck R. De Clercq E, et al. Among authors: naesens l. Nucleosides Nucleotides. 1999 Apr-May;18(4-5):759-71. doi: 10.1080/15257779908041563. Nucleosides Nucleotides. 1999. PMID: 10432678

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