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Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans.
De la Torre R, De Sola S, Pons M, Duchon A, de Lagran MM, Farré M, Fitó M, Benejam B, Langohr K, Rodriguez J, Pujadas M, Bizot JC, Cuenca A, Janel N, Catuara S, Covas MI, Blehaut H, Herault Y, Delabar JM, Dierssen M. De la Torre R, et al. Among authors: de lagran mm. Mol Nutr Food Res. 2014 Feb;58(2):278-88. doi: 10.1002/mnfr.201300325. Epub 2013 Sep 14. Mol Nutr Food Res. 2014. PMID: 24039182 Clinical Trial.
On dendrites in Down syndrome and DS murine models: a spiny way to learn.
Benavides-Piccione R, Ballesteros-Yáñez I, de Lagrán MM, Elston G, Estivill X, Fillat C, Defelipe J, Dierssen M. Benavides-Piccione R, et al. Among authors: de lagran mm. Prog Neurobiol. 2004 Oct;74(2):111-26. doi: 10.1016/j.pneurobio.2004.08.001. Prog Neurobiol. 2004. PMID: 15518956 Review.
Exploring the link between hedonic overeating and prefrontal cortex dysfunction in the Ts65Dn trisomic mouse model.
Fructuoso M, Fernández-Blanco Á, Gallego-Román A, Sierra C, de Lagrán MM, Lorenzon N, De Toma I, Langohr K, Martín-García E, Maldonado R, Dairou J, Janel N, Dierssen M. Fructuoso M, et al. Among authors: de lagran mm. Cell Mol Life Sci. 2023 Nov 21;80(12):370. doi: 10.1007/s00018-023-05009-x. Cell Mol Life Sci. 2023. PMID: 37989807 Free PMC article.
15 results