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Alterations of RAS signalling in Chinese multiple myeloma patients: absent BRAF and rare RAS mutations, but frequent inactivation of RASSF1A by transcriptional silencing or expression of a non-functional variant transcript.
Ng MH, Lau KM, Wong WS, To KW, Cheng SH, Tsang KS, Chan NP, Kho BC, Lo KW, Tong JH, Lam CW, Chan JC. Ng MH, et al. Br J Haematol. 2003 Nov;123(4):637-45. doi: 10.1046/j.1365-2141.2003.04664.x. Br J Haematol. 2003. PMID: 14616967 Free article.
4q loss is potentially an important genetic event in MM tumorigenesis: identification of a tumor suppressor gene regulated by promoter methylation at 4q13.3, platelet factor 4.
Cheng SH, Ng MH, Lau KM, Liu HS, Chan JC, Hui AB, Lo KW, Jiang H, Hou J, Chu RW, Wong WS, Chan NP, Ng HK. Cheng SH, et al. Among authors: ng hk, ng mh. Blood. 2007 Mar 1;109(5):2089-99. doi: 10.1182/blood-2006-04-018770. Epub 2006 Oct 31. Blood. 2007. PMID: 17077331 Free article.
450 results