Glick GD - Search Results

1

Effector T cells require fatty acid metabolism during murine graft-versus-host disease.

Byersdorfer CA, Tkachev V, Opipari AW, Goodell S, Swanson J, Sandquist S, Glick GD, Ferrara JL. Byersdorfer CA, et al. Among authors: glick gd. Blood. 2013 Oct 31;122(18):3230-7. doi: 10.1182/blood-2013-04-495515. Epub 2013 Sep 17. Blood. 2013. PMID: 24046012 Free PMC article.

2

Attenuation of autoimmune disease in Fas-deficient mice by treatment with a cytotoxic benzodiazepine.

Bednarski JJ, Warner RE, Rao T, Leonetti F, Yung R, Richardson BC, Johnson KJ, Ellman JA, Opipari AW Jr, Glick GD. Bednarski JJ, et al. Among authors: glick gd. Arthritis Rheum. 2003 Mar;48(3):757-66. doi: 10.1002/art.10968. Arthritis Rheum. 2003. PMID: 12632430 Free article.

3

The proapoptotic benzodiazepine Bz-423 affects the growth and survival of malignant B cells.

Boitano A, Ellman JA, Glick GD, Opipari AW Jr. Boitano A, et al. Among authors: glick gd. Cancer Res. 2003 Oct 15;63(20):6870-6. Cancer Res. 2003. PMID: 14583485

4

A novel benzodiazepine increases the sensitivity of B cells to receptor stimulation with synergistic effects on calcium signaling and apoptosis.

Bednarski JJ, Lyssiotis CA, Roush R, Boitano AE, Glick GD, Opipari AW Jr. Bednarski JJ, et al. Among authors: glick gd. J Biol Chem. 2004 Jul 9;279(28):29615-21. doi: 10.1074/jbc.M403507200. Epub 2004 May 3. J Biol Chem. 2004. PMID: 15123639 Free article.

5

Identification and validation of the mitochondrial F1F0-ATPase as the molecular target of the immunomodulatory benzodiazepine Bz-423.

Johnson KM, Chen X, Boitano A, Swenson L, Opipari AW Jr, Glick GD. Johnson KM, et al. Among authors: glick gd. Chem Biol. 2005 Apr;12(4):485-96. doi: 10.1016/j.chembiol.2005.02.012. Chem Biol. 2005. PMID: 15850986

6

The immunomodulatory benzodiazepine Bz-423 inhibits B-cell proliferation by targeting c-myc protein for rapid and specific degradation.

Sundberg TB, Ney GM, Subramanian C, Opipari AW Jr, Glick GD. Sundberg TB, et al. Among authors: glick gd. Cancer Res. 2006 Feb 1;66(3):1775-82. doi: 10.1158/0008-5472.CAN-05-3476. Cancer Res. 2006. PMID: 16452238

7

Mechanistic basis for therapeutic targeting of the mitochondrial F1F0-ATPase.

Johnson KM, Cleary J, Fierke CA, Opipari AW Jr, Glick GD. Johnson KM, et al. Among authors: glick gd. ACS Chem Biol. 2006 Jun 20;1(5):304-8. doi: 10.1021/cb600143j. ACS Chem Biol. 2006. PMID: 17163759

8

Inhibition of the mitochondrial F1F0-ATPase by ligands of the peripheral benzodiazepine receptor.

Cleary J, Johnson KM, Opipari AW Jr, Glick GD. Cleary J, et al. Among authors: glick gd. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1667-70. doi: 10.1016/j.bmcl.2006.12.102. Epub 2007 Jan 8. Bioorg Med Chem Lett. 2007. PMID: 17251020

9

7-Chloro-5-(4-hydroxyphenyl)-1-methyl-3-(naphthalen-2-ylmethyl)-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one (Bz-423), a benzodiazepine, suppresses keratinocyte proliferation and has antipsoriatic activity in the human skin-severe, combined immunodeficient mouse transplant model.

Bhagavathula N, Nerusu KC, Hanosh A, Aslam MN, Sundberg TB, Opipari AW Jr, Johnson K, Kang S, Glick GD, Varani J. Bhagavathula N, et al. Among authors: glick gd. J Pharmacol Exp Ther. 2008 Mar;324(3):938-47. doi: 10.1124/jpet.107.130955. Epub 2007 Nov 30. J Pharmacol Exp Ther. 2008. PMID: 18055879

10

Bz-423 superoxide signals apoptosis via selective activation of JNK, Bak, and Bax.

Blatt NB, Boitano AE, Lyssiotis CA, Opipari AW Jr, Glick GD. Blatt NB, et al. Among authors: glick gd. Free Radic Biol Med. 2008 Nov 1;45(9):1232-42. doi: 10.1016/j.freeradbiomed.2008.07.022. Epub 2008 Aug 3. Free Radic Biol Med. 2008. PMID: 18718527 Free PMC article.

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