Kleijn A - Search Results

1

Serum-free culture success of glial tumors is related to specific molecular profiles and expression of extracellular matrix-associated gene modules.

Balvers RK, Kleijn A, Kloezeman JJ, French PJ, Kremer A, van den Bent MJ, Dirven CM, Leenstra S, Lamfers ML. Balvers RK, et al. Among authors: kleijn a. Neuro Oncol. 2013 Dec;15(12):1684-95. doi: 10.1093/neuonc/not116. Epub 2013 Sep 17. Neuro Oncol. 2013. PMID: 24046260 Free PMC article.

2

ABT-888 enhances cytotoxic effects of temozolomide independent of MGMT status in serum free cultured glioma cells.

Balvers RK, Lamfers ML, Kloezeman JJ, Kleijn A, Berghauser Pont LM, Dirven CM, Leenstra S. Balvers RK, et al. Among authors: kleijn a. J Transl Med. 2015 Feb 26;13:74. doi: 10.1186/s12967-015-0427-y. J Transl Med. 2015. PMID: 25886061 Free PMC article.

3

The in vivo therapeutic efficacy of the oncolytic adenovirus Delta24-RGD is mediated by tumor-specific immunity.

Kleijn A, Kloezeman J, Treffers-Westerlaken E, Fulci G, Leenstra S, Dirven C, Debets R, Lamfers M. Kleijn A, et al. PLoS One. 2014 May 27;9(5):e97495. doi: 10.1371/journal.pone.0097495. eCollection 2014. PLoS One. 2014. PMID: 24866126 Free PMC article.

4

Cerebrospinal fluid biomarkers of malignancies located in the central nervous system.

Verheul C, Kleijn A, Lamfers MLM. Verheul C, et al. Among authors: kleijn a. Handb Clin Neurol. 2017;146:139-169. doi: 10.1016/B978-0-12-804279-3.00010-1. Handb Clin Neurol. 2017. PMID: 29110768 Review.

5

Oncolytic virotherapy in glioblastoma patients induces a tumor macrophage phenotypic shift leading to an altered glioblastoma microenvironment.

van den Bossche WBL, Kleijn A, Teunissen CE, Voerman JSA, Teodosio C, Noske DP, van Dongen JJM, Dirven CMF, Lamfers MLM. van den Bossche WBL, et al. Among authors: kleijn a. Neuro Oncol. 2018 Oct 9;20(11):1494-1504. doi: 10.1093/neuonc/noy082. Neuro Oncol. 2018. PMID: 29796615 Free PMC article.

6

The therapeutic efficacy of the oncolytic virus Delta24-RGD in a murine glioma model depends primarily on antitumor immunity.

Kleijn A, Kloezeman J, Treffers-Westerlaken E, Fulci G, Leenstra S, Dirven C, Debets R, Lamfers M. Kleijn A, et al. Oncoimmunology. 2014 Dec 13;3(9):e955697. doi: 10.4161/21624011.2014.955697. eCollection 2014 Oct. Oncoimmunology. 2014. PMID: 25941622 Free PMC article.

7

A Systematic Comparison Identifies an ATP-Based Viability Assay as Most Suitable Read-Out for Drug Screening in Glioma Stem-Like Cells.

Kleijn A, Kloezeman JJ, Balvers RK, van der Kaaij M, Dirven CM, Leenstra S, Lamfers ML. Kleijn A, et al. Stem Cells Int. 2016;2016:5623235. doi: 10.1155/2016/5623235. Epub 2016 May 5. Stem Cells Int. 2016. PMID: 27274737 Free PMC article.

8

The HDAC Inhibitors Scriptaid and LBH589 Combined with the Oncolytic Virus Delta24-RGD Exert Enhanced Anti-Tumor Efficacy in Patient-Derived Glioblastoma Cells.

Berghauser Pont LM, Kleijn A, Kloezeman JJ, van den Bossche W, Kaufmann JK, de Vrij J, Leenstra S, Dirven CM, Lamfers ML. Berghauser Pont LM, et al. Among authors: kleijn a. PLoS One. 2015 May 18;10(5):e0127058. doi: 10.1371/journal.pone.0127058. eCollection 2015. PLoS One. 2015. PMID: 25993039 Free PMC article.

9

The Sequence of Delta24-RGD and TMZ Administration in Malignant Glioma Affects the Role of CD8⁺T Cell Anti-tumor Activity.

Kleijn A, van den Bossche W, Haefner ES, Belcaid Z, Burghoorn-Maas C, Kloezeman JJ, Pas SD, Leenstra S, Debets R, de Vrij J, Dirven CMF, Lamfers MLM. Kleijn A, et al. Mol Ther Oncolytics. 2017 Mar 1;5:11-19. doi: 10.1016/j.omto.2017.02.002. eCollection 2017 Jun 16. Mol Ther Oncolytics. 2017. PMID: 28480325 Free PMC article.

10

Convection Enhanced Delivery of the Oncolytic Adenovirus Delta24-RGD in Patients with Recurrent GBM: A Phase I Clinical Trial Including Correlative Studies.

van Putten EHP, Kleijn A, van Beusechem VW, Noske D, Lamers CHJ, de Goede AL, Idema S, Hoefnagel D, Kloezeman JJ, Fueyo J, Lang FF, Teunissen CE, Vernhout RM, Bakker C, Gerritsen W, Curiel DT, Vulto A, Lamfers MLM, Dirven CMF. van Putten EHP, et al. Among authors: kleijn a. Clin Cancer Res. 2022 Apr 14;28(8):1572-1585. doi: 10.1158/1078-0432.CCR-21-3324. Clin Cancer Res. 2022. PMID: 35176144 Free PMC article. Clinical Trial.

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