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Page 1
Inventing new medicines: The FGF21 story.
Kharitonenkov A, Adams AC. Kharitonenkov A, et al. Among authors: adams ac. Mol Metab. 2013 Dec 27;3(3):221-9. doi: 10.1016/j.molmet.2013.12.003. eCollection 2014 Jun. Mol Metab. 2013. PMID: 24749049 Free PMC article. Review.
The anti-obesity effect of FGF19 does not require UCP1-dependent thermogenesis.
Antonellis PJ, Droz BA, Cosgrove R, O'Farrell LS, Coskun T, Perfield JW 2nd, Bauer S, Wade M, Chouinard TE, Brozinick JT, Adams AC, Samms RJ. Antonellis PJ, et al. Among authors: adams ac. Mol Metab. 2019 Dec;30:131-139. doi: 10.1016/j.molmet.2019.09.006. Epub 2019 Sep 29. Mol Metab. 2019. PMID: 31767164 Free PMC article.
Fundamentals of FGF19 & FGF21 action in vitro and in vivo.
Adams AC, Coskun T, Rovira AR, Schneider MA, Raches DW, Micanovic R, Bina HA, Dunbar JD, Kharitonenkov A. Adams AC, et al. PLoS One. 2012;7(5):e38438. doi: 10.1371/journal.pone.0038438. Epub 2012 May 31. PLoS One. 2012. PMID: 22675463 Free PMC article.
FGF21 requires βklotho to act in vivo.
Adams AC, Cheng CC, Coskun T, Kharitonenkov A. Adams AC, et al. PLoS One. 2012;7(11):e49977. doi: 10.1371/journal.pone.0049977. Epub 2012 Nov 27. PLoS One. 2012. PMID: 23209629 Free PMC article.
Central Fibroblast Growth Factor 21 Browns White Fat via Sympathetic Action in Male Mice.
Douris N, Stevanovic DM, Fisher FM, Cisu TI, Chee MJ, Nguyen NL, Zarebidaki E, Adams AC, Kharitonenkov A, Flier JS, Bartness TJ, Maratos-Flier E. Douris N, et al. Among authors: adams ac. Endocrinology. 2015 Jul;156(7):2470-81. doi: 10.1210/en.2014-2001. Epub 2015 Apr 29. Endocrinology. 2015. PMID: 25924103 Free PMC article.
Discrete Aspects of FGF21 In Vivo Pharmacology Do Not Require UCP1.
Samms RJ, Smith DP, Cheng CC, Antonellis PP, Perfield JW 2nd, Kharitonenkov A, Gimeno RE, Adams AC. Samms RJ, et al. Among authors: adams ac. Cell Rep. 2015 May 19;11(7):991-9. doi: 10.1016/j.celrep.2015.04.046. Epub 2015 May 5. Cell Rep. 2015. PMID: 25956583 Free article.
121 results