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Hepatic signaling by the mechanistic target of rapamycin complex 2 (mTORC2).
Lamming DW, Demirkan G, Boylan JM, Mihaylova MM, Peng T, Ferreira J, Neretti N, Salomon A, Sabatini DM, Gruppuso PA. Lamming DW, et al. Among authors: sabatini dm. FASEB J. 2014 Jan;28(1):300-15. doi: 10.1096/fj.13-237743. Epub 2013 Sep 26. FASEB J. 2014. PMID: 24072782 Free PMC article.
A radical role for TOR in longevity.
Lamming DW, Sabatini DM. Lamming DW, et al. Among authors: sabatini dm. Cell Metab. 2011 Jun 8;13(6):617-8. doi: 10.1016/j.cmet.2011.05.006. Cell Metab. 2011. PMID: 21641542 Free PMC article.
mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake.
Yilmaz ÖH, Katajisto P, Lamming DW, Gültekin Y, Bauer-Rowe KE, Sengupta S, Birsoy K, Dursun A, Yilmaz VO, Selig M, Nielsen GP, Mino-Kenudson M, Zukerberg LR, Bhan AK, Deshpande V, Sabatini DM. Yilmaz ÖH, et al. Among authors: sabatini dm. Nature. 2012 Jun 28;486(7404):490-5. doi: 10.1038/nature11163. Nature. 2012. PMID: 22722868 Free PMC article.
Rapalogs and mTOR inhibitors as anti-aging therapeutics.
Lamming DW, Ye L, Sabatini DM, Baur JA. Lamming DW, et al. Among authors: sabatini dm. J Clin Invest. 2013 Mar;123(3):980-9. doi: 10.1172/JCI64099. Epub 2013 Mar 1. J Clin Invest. 2013. PMID: 23454761 Free PMC article. Review.
291 results