Hunter R - Search Results

1

In vitro antimalarial activity, β-haematin inhibition and structure-activity relationships in a series of quinoline triazoles.

Joshi MC, Wicht KJ, Taylor D, Hunter R, Smith PJ, Egan TJ. Joshi MC, et al. Among authors: hunter r. Eur J Med Chem. 2013 Nov;69:338-47. doi: 10.1016/j.ejmech.2013.08.046. Epub 2013 Sep 12. Eur J Med Chem. 2013. PMID: 24077524

2

Structure-function relationships in aminoquinolines: effect of amino and chloro groups on quinoline-hematin complex formation, inhibition of beta-hematin formation, and antiplasmodial activity.

Egan TJ, Hunter R, Kaschula CH, Marques HM, Misplon A, Walden J. Egan TJ, et al. Among authors: hunter r. J Med Chem. 2000 Jan 27;43(2):283-91. doi: 10.1021/jm990437l. J Med Chem. 2000. PMID: 10649984

3

Structure-activity relationships in 4-aminoquinoline antiplasmodials. The role of the group at the 7-position.

Kaschula CH, Egan TJ, Hunter R, Basilico N, Parapini S, Taramelli D, Pasini E, Monti D. Kaschula CH, et al. Among authors: hunter r. J Med Chem. 2002 Aug 1;45(16):3531-9. doi: 10.1021/jm020858u. J Med Chem. 2002. PMID: 12139464

4

Current developments in the synthesis and biological activity of HIV-1 double-drug inhibitors.

Muhanji CI, Hunter R. Muhanji CI, et al. Among authors: hunter r. Curr Med Chem. 2007;14(11):1207-20. doi: 10.2174/092986707780597952. Curr Med Chem. 2007. PMID: 17504141 Review.

5

Substituted ajoenes as novel anti-cancer agents.

Hunter R, Kaschula CH, Parker IM, Caira MR, Richards P, Travis S, Taute F, Qwebani T. Hunter R, et al. Bioorg Med Chem Lett. 2008 Oct 1;18(19):5277-9. doi: 10.1016/j.bmcl.2008.08.056. Epub 2008 Aug 22. Bioorg Med Chem Lett. 2008. PMID: 18774712

6

C-2-aryl O-substituted HI-236 derivatives as non-nucleoside HIV-1 reverse-transcriptase inhibitors.

Hunter R, Younis Y, Muhanji CI, Curtin TL, Naidoo KJ, Petersen M, Bailey CM, Basavapathruni A, Anderson KS. Hunter R, et al. Bioorg Med Chem. 2008 Dec 15;16(24):10270-80. doi: 10.1016/j.bmc.2008.10.048. Epub 2008 Nov 1. Bioorg Med Chem. 2008. PMID: 18996020 Free PMC article.

7

Interference with hemozoin formation represents an important mechanism of schistosomicidal action of antimalarial quinoline methanols.

Corrêa Soares JB, Menezes D, Vannier-Santos MA, Ferreira-Pereira A, Almeida GT, Venancio TM, Verjovski-Almeida S, Zishiri VK, Kuter D, Hunter R, Egan TJ, Oliveira MF. Corrêa Soares JB, et al. Among authors: hunter r. PLoS Negl Trop Dis. 2009 Jul 14;3(7):e477. doi: 10.1371/journal.pntd.0000477. PLoS Negl Trop Dis. 2009. PMID: 19597543 Free PMC article.

8

Conjugates of plumbagin and phenyl-2-amino-1-thioglucoside inhibit MshB, a deacetylase involved in the biosynthesis of mycothiol.

Gammon DW, Steenkamp DJ, Mavumengwana V, Marakalala MJ, Mudzunga TT, Hunter R, Munyololo M. Gammon DW, et al. Among authors: hunter r. Bioorg Med Chem. 2010 Apr 1;18(7):2501-14. doi: 10.1016/j.bmc.2010.02.049. Epub 2010 Mar 1. Bioorg Med Chem. 2010. PMID: 20304659

9

[d4U]-spacer-[HI-236] double-drug inhibitors of HIV-1 reverse-transcriptase.

Younis Y, Hunter R, Muhanji CI, Hale I, Singh R, Bailey CM, Sullivan TJ, Anderson KS. Younis Y, et al. Among authors: hunter r. Bioorg Med Chem. 2010 Jul 1;18(13):4661-73. doi: 10.1016/j.bmc.2010.05.025. Epub 2010 May 11. Bioorg Med Chem. 2010. PMID: 20605472 Free PMC article.

10

Synthesis and anti-prion activity evaluation of aminoquinoline analogues.

Macedo B, Kaschula CH, Hunter R, Chaves JA, van der Merwe JD, Silva JL, Egan TJ, Cordeiro Y. Macedo B, et al. Among authors: hunter r. Eur J Med Chem. 2010 Nov;45(11):5468-73. doi: 10.1016/j.ejmech.2010.07.054. Epub 2010 Aug 6. Eur J Med Chem. 2010. PMID: 20797807

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