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The CSF3R T618I mutation causes a lethal neutrophilic neoplasia in mice that is responsive to therapeutic JAK inhibition.
Blood. 2013 Nov 21;122(22):3628-31. doi: 10.1182/blood-2013-06-509976. Epub 2013 Sep 30.
Blood. 2013.
PMID: 24081659
Free PMC article.
JAK2(V617I) results in cytokine hypersensitivity without causing an overt myeloproliferative disorder in a mouse transduction-transplantation model.
Brooks SA, Luty SB, Lai HY, Morse SJ, Nguyen TK, Royer LR, Agarwal A, Druker BJ, Fleischman AG.
Brooks SA, et al. Among authors: royer lr.
Exp Hematol. 2016 Jan;44(1):24-9.e1. doi: 10.1016/j.exphem.2015.09.006. Epub 2015 Oct 13.
Exp Hematol. 2016.
PMID: 26458983
Free PMC article.
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