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Paracrine activation of WNT/β-catenin pathway in uterine leiomyoma stem cells promotes tumor growth.
Ono M, Yin P, Navarro A, Moravek MB, Coon JS 5th, Druschitz SA, Serna VA, Qiang W, Brooks DC, Malpani SS, Ma J, Ercan CM, Mittal N, Monsivais D, Dyson MT, Yemelyanov A, Maruyama T, Chakravarti D, Kim JJ, Kurita T, Gottardi CJ, Bulun SE. Ono M, et al. Among authors: gottardi cj. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):17053-8. doi: 10.1073/pnas.1313650110. Epub 2013 Sep 30. Proc Natl Acad Sci U S A. 2013. PMID: 24082114 Free PMC article. Clinical Trial.
Alveolitis in severe SARS-CoV-2 pneumonia is driven by self-sustaining circuits between infected alveolar macrophages and T cells.
Grant RA, Morales-Nebreda L, Markov NS, Swaminathan S, Guzman ER, Abbott DA, Donnelly HK, Donayre A, Goldberg IA, Klug ZM, Borkowski N, Lu Z, Kihshen H, Politanska Y, Sichizya L, Kang M, Shilatifard A, Qi C, Argento AC, Kruser JM, Malsin ES, Pickens CO, Smith S, Walter JM, Pawlowski AE, Schneider D, Nannapaneni P, Abdala-Valencia H, Bharat A, Gottardi CJ, Budinger GS, Misharin AV, Singer BD, Wunderink RG; NU SCRIPT Study Investigators. Grant RA, et al. Among authors: gottardi cj. bioRxiv [Preprint]. 2020 Aug 7:2020.08.05.238188. doi: 10.1101/2020.08.05.238188. bioRxiv. 2020. Update in: Nature. 2021 Feb;590(7847):635-641. doi: 10.1038/s41586-020-03148-w PMID: 34013276 Free PMC article. Updated. Preprint.
Inhibition of canonical WNT signaling attenuates human leiomyoma cell growth.
Ono M, Yin P, Navarro A, Moravek MB, Coon V JS, Druschitz SA, Gottardi CJ, Bulun SE. Ono M, et al. Among authors: gottardi cj. Fertil Steril. 2014 May;101(5):1441-9. doi: 10.1016/j.fertnstert.2014.01.017. Epub 2014 Feb 15. Fertil Steril. 2014. PMID: 24534281 Free PMC article.
α-Catenin is an inhibitor of transcription.
Daugherty RL, Serebryannyy L, Yemelyanov A, Flozak AS, Yu HJ, Kosak ST, deLanerolle P, Gottardi CJ. Daugherty RL, et al. Among authors: gottardi cj. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5260-5. doi: 10.1073/pnas.1308663111. Epub 2014 Mar 25. Proc Natl Acad Sci U S A. 2014. PMID: 24706864 Free PMC article.
103 results