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Febuxostat ameliorates secondary progressive experimental autoimmune encephalomyelitis by restoring mitochondrial energy production in a GOT2-dependent manner.
Honorat JA, Nakatsuji Y, Shimizu M, Kinoshita M, Sumi-Akamaru H, Sasaki T, Takata K, Koda T, Namba A, Yamashita K, Sanda E, Sakaguchi M, Kumanogoh A, Shirakura T, Tamura M, Sakoda S, Mochizuki H, Okuno T. Honorat JA, et al. Among authors: tamura m. PLoS One. 2017 Nov 6;12(11):e0187215. doi: 10.1371/journal.pone.0187215. eCollection 2017. PLoS One. 2017. PMID: 29107957 Free PMC article.
Activity of xanthine oxidase in plasma correlates with indices of insulin resistance and liver dysfunction in patients with type 2 diabetes mellitus and metabolic syndrome: A pilot exploratory study.
Sunagawa S, Shirakura T, Hokama N, Kozuka C, Yonamine M, Namba T, Morishima S, Nakachi S, Nishi Y, Ikema T, Okamoto S, Matsui C, Hase N, Tamura M, Shimabukuro M, Masuzaki H. Sunagawa S, et al. Among authors: tamura m. J Diabetes Investig. 2019 Jan;10(1):94-103. doi: 10.1111/jdi.12870. Epub 2018 Jul 7. J Diabetes Investig. 2019. PMID: 29862667 Free PMC article.
Uric acid secretion from adipose tissue and its increase in obesity.
Tsushima Y, Nishizawa H, Tochino Y, Nakatsuji H, Sekimoto R, Nagao H, Shirakura T, Kato K, Imaizumi K, Takahashi H, Tamura M, Maeda N, Funahashi T, Shimomura I. Tsushima Y, et al. Among authors: tamura m. J Biol Chem. 2013 Sep 20;288(38):27138-27149. doi: 10.1074/jbc.M113.485094. Epub 2013 Aug 2. J Biol Chem. 2013. PMID: 23913681 Free PMC article.
A pilot assessment of xanthine oxidase activity in plasma from patients with hematological malignancies using a highly sensitive assay.
Hokama N, Shirakura T, Sunagawa S, Morishima S, Nakachi S, Nishi Y, Murayama Y, Matsui C, Hase N, Tamura M, Okamoto S, Shimabukuro M, Nakamura K, Masuzaki H. Hokama N, et al. Among authors: tamura m. Hematol Oncol. 2019 Oct;37(4):527-530. doi: 10.1002/hon.2659. Epub 2019 Aug 27. Hematol Oncol. 2019. PMID: 31359444 Clinical Trial. No abstract available.
3,068 results