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Poly (ADP-ribose) polymerase-1 is a key mediator of liver inflammation and fibrosis.
Mukhopadhyay P, Rajesh M, Cao Z, Horváth B, Park O, Wang H, Erdelyi K, Holovac E, Wang Y, Liaudet L, Hamdaoui N, Lafdil F, Haskó G, Szabo C, Boulares AH, Gao B, Pacher P. Mukhopadhyay P, et al. Among authors: rajesh m. Hepatology. 2014 May;59(5):1998-2009. doi: 10.1002/hep.26763. Epub 2014 Apr 1. Hepatology. 2014. PMID: 24089324 Free PMC article.
PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis.
Mukhopadhyay P, Horváth B, Rajesh M, Varga ZV, Gariani K, Ryu D, Cao Z, Holovac E, Park O, Zhou Z, Xu MJ, Wang W, Godlewski G, Paloczi J, Nemeth BT, Persidsky Y, Liaudet L, Haskó G, Bai P, Boulares AH, Auwerx J, Gao B, Pacher P. Mukhopadhyay P, et al. Among authors: rajesh m. J Hepatol. 2017 Mar;66(3):589-600. doi: 10.1016/j.jhep.2016.10.023. Epub 2016 Oct 29. J Hepatol. 2017. PMID: 27984176
Poly(ADP-ribose)polymerase inhibition decreases angiogenesis.
Rajesh M, Mukhopadhyay P, Godlewski G, Bátkai S, Haskó G, Liaudet L, Pacher P. Rajesh M, et al. Biochem Biophys Res Commun. 2006 Dec 1;350(4):1056-62. doi: 10.1016/j.bbrc.2006.09.160. Epub 2006 Oct 9. Biochem Biophys Res Commun. 2006. PMID: 17046715 Free PMC article.
216 results