Halperin JA - Search Results

1

Small-Molecule targeting of translation initiation for cancer therapy.

Aktas BH, Qiao Y, Ozdelen E, Schubert R, Sevinc S, Harbinski F, Grubissich L, Singer S, Halperin JA. Aktas BH, et al. Among authors: halperin ja. Oncotarget. 2013 Oct;4(10):1606-17. doi: 10.18632/oncotarget.1186. Oncotarget. 2013. PMID: 24091475 Free PMC article.

2

Depletion of intracellular Ca2+ stores, phosphorylation of eIF2alpha, and sustained inhibition of translation initiation mediate the anticancer effects of clotrimazole.

Aktas H, Flückiger R, Acosta JA, Savage JM, Palakurthi SS, Halperin JA. Aktas H, et al. Among authors: halperin ja. Proc Natl Acad Sci U S A. 1998 Jul 7;95(14):8280-5. doi: 10.1073/pnas.95.14.8280. Proc Natl Acad Sci U S A. 1998. PMID: 9653178 Free PMC article.

3

Inhibition of translation initiation mediates the anticancer effect of the n-3 polyunsaturated fatty acid eicosapentaenoic acid.

Palakurthi SS, Flückiger R, Aktas H, Changolkar AK, Shahsafaei A, Harneit S, Kilic E, Halperin JA. Palakurthi SS, et al. Among authors: halperin ja. Cancer Res. 2000 Jun 1;60(11):2919-25. Cancer Res. 2000. PMID: 10850438

4

Anticancer effects of thiazolidinediones are independent of peroxisome proliferator-activated receptor gamma and mediated by inhibition of translation initiation.

Palakurthi SS, Aktas H, Grubissich LM, Mortensen RM, Halperin JA. Palakurthi SS, et al. Among authors: halperin ja. Cancer Res. 2001 Aug 15;61(16):6213-8. Cancer Res. 2001. PMID: 11507074

5

Deficiency of the mouse complement regulatory protein mCd59b results in spontaneous hemolytic anemia with platelet activation and progressive male infertility.

Qin X, Krumrei N, Grubissich L, Dobarro M, Aktas H, Perez G, Halperin JA. Qin X, et al. Among authors: halperin ja. Immunity. 2003 Feb;18(2):217-27. doi: 10.1016/s1074-7613(03)00022-0. Immunity. 2003. PMID: 12594949 Free article.

6

Structure-activity requirements for the antiproliferative effect of troglitazone derivatives mediated by depletion of intracellular calcium.

Fan YH, Chen H, Natarajan A, Guo Y, Harbinski F, Iyasere J, Christ W, Aktas H, Halperin JA. Fan YH, et al. Among authors: halperin ja. Bioorg Med Chem Lett. 2004 May 17;14(10):2547-50. doi: 10.1016/j.bmcl.2004.02.087. Bioorg Med Chem Lett. 2004. PMID: 15109648

7

Glycation inactivation of the complement regulatory protein CD59: a possible role in the pathogenesis of the vascular complications of human diabetes.

Qin X, Goldfine A, Krumrei N, Grubissich L, Acosta J, Chorev M, Hays AP, Halperin JA. Qin X, et al. Among authors: halperin ja. Diabetes. 2004 Oct;53(10):2653-61. doi: 10.2337/diabetes.53.10.2653. Diabetes. 2004. PMID: 15448097

8

Synthesis and biological evaluation of thiazolidine-2,4-dione and 2,4-thione derivatives as inhibitors of translation initiation.

Chen H, Fan YH, Natarajan A, Guo Y, Iyasere J, Harbinski F, Luus L, Christ W, Aktas H, Halperin JA. Chen H, et al. Among authors: halperin ja. Bioorg Med Chem Lett. 2004 Nov 1;14(21):5401-5. doi: 10.1016/j.bmcl.2004.08.017. Bioorg Med Chem Lett. 2004. PMID: 15454234

9

Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G.

Moerke NJ, Aktas H, Chen H, Cantel S, Reibarkh MY, Fahmy A, Gross JD, Degterev A, Yuan J, Chorev M, Halperin JA, Wagner G. Moerke NJ, et al. Among authors: halperin ja. Cell. 2007 Jan 26;128(2):257-67. doi: 10.1016/j.cell.2006.11.046. Cell. 2007. PMID: 17254965 Free article.

10

Generation and phenotyping of mCd59a and mCd59b double-knockout mice.

Qin X, Hu W, Song W, Grubissich L, Hu X, Wu G, Ferris S, Dobarro M, Halperin JA. Qin X, et al. Among authors: halperin ja. Am J Hematol. 2009 Feb;84(2):65-70. doi: 10.1002/ajh.21319. Am J Hematol. 2009. PMID: 19051264 Free PMC article.

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