Ramesh T - Search Results

1

A new zebrafish model produced by TILLING of SOD1-related amyotrophic lateral sclerosis replicates key features of the disease and represents a tool for in vivo therapeutic screening.

Da Costa MM, Allen CE, Higginbottom A, Ramesh T, Shaw PJ, McDermott CJ. Da Costa MM, et al. Among authors: ramesh t. Dis Model Mech. 2014 Jan;7(1):73-81. doi: 10.1242/dmm.012013. Epub 2013 Oct 2. Dis Model Mech. 2014. PMID: 24092880 Free PMC article.

2

A genetic model of amyotrophic lateral sclerosis in zebrafish displays phenotypic hallmarks of motoneuron disease.

Ramesh T, Lyon AN, Pineda RH, Wang C, Janssen PM, Canan BD, Burghes AH, Beattie CE. Ramesh T, et al. Dis Model Mech. 2010 Sep-Oct;3(9-10):652-62. doi: 10.1242/dmm.005538. Epub 2010 May 26. Dis Model Mech. 2010. PMID: 20504969 Free PMC article.

3

Early interneuron dysfunction in ALS: insights from a mutant sod1 zebrafish model.

McGown A, McDearmid JR, Panagiotaki N, Tong H, Al Mashhadi S, Redhead N, Lyon AN, Beattie CE, Shaw PJ, Ramesh TM. McGown A, et al. Ann Neurol. 2013 Feb;73(2):246-58. doi: 10.1002/ana.23780. Epub 2012 Dec 31. Ann Neurol. 2013. PMID: 23281025 Free PMC article.

4

Tardbpl splicing rescues motor neuron and axonal development in a mutant tardbp zebrafish.

Hewamadduma CA, Grierson AJ, Ma TP, Pan L, Moens CB, Ingham PW, Ramesh T, Shaw PJ. Hewamadduma CA, et al. Among authors: ramesh t. Hum Mol Genet. 2013 Jun 15;22(12):2376-86. doi: 10.1093/hmg/ddt082. Epub 2013 Feb 19. Hum Mol Genet. 2013. PMID: 23427147 Free PMC article.

5

Axonal Transport Defects in a Mitofusin 2 Loss of Function Model of Charcot-Marie-Tooth Disease in Zebrafish.

Chapman AL, Bennett EJ, Ramesh TM, De Vos KJ, Grierson AJ. Chapman AL, et al. PLoS One. 2013 Jun 26;8(6):e67276. doi: 10.1371/journal.pone.0067276. Print 2013. PLoS One. 2013. PMID: 23840650 Free PMC article.

6

Abnormalities in whisking behaviour are associated with lesions in brain stem nuclei in a mouse model of amyotrophic lateral sclerosis.

Grant RA, Sharp PS, Kennerley AJ, Berwick J, Grierson A, Ramesh T, Prescott TJ. Grant RA, et al. Among authors: ramesh t. Behav Brain Res. 2014 Feb 1;259:274-83. doi: 10.1016/j.bbr.2013.11.002. Epub 2013 Nov 13. Behav Brain Res. 2014. PMID: 24239688 Free article.

7

A zebrafish model exemplifies the long preclinical period of motor neuron disease.

Ramesh TM, Shaw PJ, McDearmid J. Ramesh TM, et al. J Neurol Neurosurg Psychiatry. 2014 Nov;85(11):1288-9. doi: 10.1136/jnnp-2014-308288. Epub 2014 Jun 26. J Neurol Neurosurg Psychiatry. 2014. PMID: 24970908 Free PMC article. No abstract available.

8

ZNStress: a high-throughput drug screening protocol for identification of compounds modulating neuronal stress in the transgenic mutant sod1G93R zebrafish model of amyotrophic lateral sclerosis.

McGown A, Shaw DP, Ramesh T. McGown A, et al. Among authors: ramesh t. Mol Neurodegener. 2016 Jul 26;11(1):56. doi: 10.1186/s13024-016-0122-3. Mol Neurodegener. 2016. PMID: 27460825 Free PMC article.

9

Animal models of multiple sclerosis: From rodents to zebrafish.

Burrows DJ, McGown A, Jain SA, De Felice M, Ramesh TM, Sharrack B, Majid A. Burrows DJ, et al. Mult Scler. 2019 Mar;25(3):306-324. doi: 10.1177/1352458518805246. Epub 2018 Oct 15. Mult Scler. 2019. PMID: 30319015 Review.

10

Stable transgenic C9orf72 zebrafish model key aspects of the ALS/FTD phenotype and reveal novel pathological features.

Shaw MP, Higginbottom A, McGown A, Castelli LM, James E, Hautbergue GM, Shaw PJ, Ramesh TM. Shaw MP, et al. Acta Neuropathol Commun. 2018 Nov 19;6(1):125. doi: 10.1186/s40478-018-0629-7. Acta Neuropathol Commun. 2018. PMID: 30454072 Free PMC article.

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