Stavnezer J - Search Results

1

A DNA break- and phosphorylation-dependent positive feedback loop promotes immunoglobulin class-switch recombination.

Vuong BQ, Herrick-Reynolds K, Vaidyanathan B, Pucella JN, Ucher AJ, Donghia NM, Gu X, Nicolas L, Nowak U, Rahman N, Strout MP, Mills KD, Stavnezer J, Chaudhuri J. Vuong BQ, et al. Among authors: stavnezer j. Nat Immunol. 2013 Nov;14(11):1183-1189. doi: 10.1038/ni.2732. Epub 2013 Oct 6. Nat Immunol. 2013. PMID: 24097111 Free PMC article.

2

AID recruits UNG and Msh2 to Ig switch regions dependent upon the AID C terminus [corrected].

Ranjit S, Khair L, Linehan EK, Ucher AJ, Chakrabarti M, Schrader CE, Stavnezer J. Ranjit S, et al. Among authors: stavnezer j. J Immunol. 2011 Sep 1;187(5):2464-75. doi: 10.4049/jimmunol.1101406. Epub 2011 Jul 29. J Immunol. 2011. PMID: 21804017 Free PMC article.

3

Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase.

Hasham MG, Snow KJ, Donghia NM, Branca JA, Lessard MD, Stavnezer J, Shopland LS, Mills KD. Hasham MG, et al. Among authors: stavnezer j. J Immunol. 2012 Sep 1;189(5):2374-82. doi: 10.4049/jimmunol.1200414. Epub 2012 Jul 23. J Immunol. 2012. PMID: 22826323 Free PMC article.

4

ATM increases activation-induced cytidine deaminase activity at downstream S regions during class-switch recombination.

Khair L, Guikema JE, Linehan EK, Ucher AJ, Leus NG, Ogilvie C, Lou Z, Schrader CE, Stavnezer J. Khair L, et al. Among authors: stavnezer j. J Immunol. 2014 May 15;192(10):4887-96. doi: 10.4049/jimmunol.1303481. Epub 2014 Apr 11. J Immunol. 2014. PMID: 24729610 Free PMC article.

5

Individual substitution mutations in the AID C terminus that ablate IgH class switch recombination.

Kadungure T, Ucher AJ, Linehan EK, Schrader CE, Stavnezer J. Kadungure T, et al. Among authors: stavnezer j. PLoS One. 2015 Aug 12;10(8):e0134397. doi: 10.1371/journal.pone.0134397. eCollection 2015. PLoS One. 2015. PMID: 26267846 Free PMC article.

6

Reassessment of the role of Mut S homolog 5 in Ig class switch recombination shows lack of involvement in cis- and trans-switching.

Guikema JE, Schrader CE, Leus NG, Ucher A, Linehan EK, Werling U, Edelmann W, Stavnezer J. Guikema JE, et al. Among authors: stavnezer j. J Immunol. 2008 Dec 15;181(12):8450-9. doi: 10.4049/jimmunol.181.12.8450. J Immunol. 2008. PMID: 19050263 Free PMC article.

7

Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig Loci in activated B cells.

Staszewski O, Baker RE, Ucher AJ, Martier R, Stavnezer J, Guikema JE. Staszewski O, et al. Among authors: stavnezer j. Mol Cell. 2011 Jan 21;41(2):232-42. doi: 10.1016/j.molcel.2011.01.007. Mol Cell. 2011. PMID: 21255732 Free PMC article.

8

The DNA glycosylases Ogg1 and Nth1 do not contribute to Ig class switching in activated mouse splenic B cells.

Ucher AJ, Linehan EK, Teebor GW, Schrader CE, Stavnezer J. Ucher AJ, et al. Among authors: stavnezer j. PLoS One. 2012;7(4):e36061. doi: 10.1371/journal.pone.0036061. Epub 2012 Apr 20. PLoS One. 2012. PMID: 22536455 Free PMC article.

9

DNA polymerases β and λ do not directly affect Ig variable region somatic hypermutation although their absence reduces the frequency of mutations.

Schrader CE, Linehan EK, Ucher AJ, Bertocci B, Stavnezer J. Schrader CE, et al. Among authors: stavnezer j. DNA Repair (Amst). 2013 Dec;12(12):1087-93. doi: 10.1016/j.dnarep.2013.09.002. Epub 2013 Sep 29. DNA Repair (Amst). 2013. PMID: 24084171 Free PMC article.

10

Differential expression of APE1 and APE2 in germinal centers promotes error-prone repair and A:T mutations during somatic hypermutation.

Stavnezer J, Linehan EK, Thompson MR, Habboub G, Ucher AJ, Kadungure T, Tsuchimoto D, Nakabeppu Y, Schrader CE. Stavnezer J, et al. Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9217-22. doi: 10.1073/pnas.1405590111. Epub 2014 Jun 9. Proc Natl Acad Sci U S A. 2014. PMID: 24927551 Free PMC article.

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