Roth BL - Search Results

1

Discovery of an in vivo chemical probe of the lysine methyltransferases G9a and GLP.

Liu F, Barsyte-Lovejoy D, Li F, Xiong Y, Korboukh V, Huang XP, Allali-Hassani A, Janzen WP, Roth BL, Frye SV, Arrowsmith CH, Brown PJ, Vedadi M, Jin J. Liu F, et al. Among authors: roth bl. J Med Chem. 2013 Nov 14;56(21):8931-42. doi: 10.1021/jm401480r. Epub 2013 Oct 31. J Med Chem. 2013. PMID: 24102134 Free PMC article.

2

A structure-affinity study of the binding of 4-substituted analogues of 1-(2,5-dimethoxyphenyl)-2-aminopropane at 5-HT2 serotonin receptors.

Seggel MR, Yousif MY, Lyon RA, Titeler M, Roth BL, Suba EA, Glennon RA. Seggel MR, et al. Among authors: roth bl. J Med Chem. 1990 Mar;33(3):1032-6. doi: 10.1021/jm00165a023. J Med Chem. 1990. PMID: 2308135

3

1-(2,5-Dimethoxy-4-(trifluoromethyl)phenyl)-2-aminopropane: a potent serotonin 5-HT2A/2C agonist.

Nichols DE, Frescas S, Marona-Lewicka D, Huang X, Roth BL, Gudelsky GA, Nash JF. Nichols DE, et al. Among authors: roth bl. J Med Chem. 1994 Dec 9;37(25):4346-51. doi: 10.1021/jm00051a011. J Med Chem. 1994. PMID: 7996545

4

2-Substituted tryptamines: agents with selectivity for 5-HT(6) serotonin receptors.

Glennon RA, Lee M, Rangisetty JB, Dukat M, Roth BL, Savage JE, McBride A, Rauser L, Hufeisen S, Lee DK. Glennon RA, et al. Among authors: roth bl. J Med Chem. 2000 Mar 9;43(5):1011-8. doi: 10.1021/jm990550b. J Med Chem. 2000. PMID: 10715164

5

N1-(Benzenesulfonyl)tryptamines as novel 5-HT6 antagonists.

Tsai Y, Dukat M, Slassi A, MacLean N, Demchyshyn L, Savage JE, Roth BL, Hufesein S, Lee M, Glennon RA. Tsai Y, et al. Among authors: roth bl. Bioorg Med Chem Lett. 2000 Oct 16;10(20):2295-9. doi: 10.1016/s0960-894x(00)00453-4. Bioorg Med Chem Lett. 2000. PMID: 11055342

6

Geometry-affinity relationships of the selective serotonin receptor ligand 9-(aminomethyl)-9,10-dihydroanthracene.

Runyon SP, Peddi S, Savage JE, Roth BL, Glennon RA, Westkaemper RB. Runyon SP, et al. Among authors: roth bl. J Med Chem. 2002 Apr 11;45(8):1656-64. doi: 10.1021/jm010354g. J Med Chem. 2002. PMID: 11931619

7

1,2,3,4-tetrahydrocarbazoles as 5-HT6 serotonin receptor ligands.

Chang-Fong J, Rangisetty JB, Dukat M, Setola V, Raffay T, Roth B, Glennon RA. Chang-Fong J, et al. Bioorg Med Chem Lett. 2004 Apr 19;14(8):1961-4. doi: 10.1016/j.bmcl.2004.01.071. Bioorg Med Chem Lett. 2004. PMID: 15050637

8

Interaction of chiral MS-245 analogs at h5-HT6 receptors.

Abate C, Kolanos R, Dukat M, Setola V, Roth BL, Glennon RA. Abate C, et al. Among authors: roth bl. Bioorg Med Chem Lett. 2005 Aug 1;15(15):3510-3. doi: 10.1016/j.bmcl.2005.05.092. Bioorg Med Chem Lett. 2005. PMID: 15990303

9

Synthesis and structure-activity relationships of 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine analogues as potent, noncompetitive metabotropic glutamate receptor subtype 5 antagonists; search for cocaine medications.

Iso Y, Grajkowska E, Wroblewski JT, Davis J, Goeders NE, Johnson KM, Sanker S, Roth BL, Tueckmantel W, Kozikowski AP. Iso Y, et al. Among authors: roth bl. J Med Chem. 2006 Feb 9;49(3):1080-100. doi: 10.1021/jm050570f. J Med Chem. 2006. PMID: 16451073

10

Binding of sulfonyl-containing arylalkylamines at human 5-HT6 serotonin receptors.

Sikazwe D, Bondarev ML, Dukat M, Rangisetty JB, Roth BL, Glennon RA. Sikazwe D, et al. Among authors: roth bl. J Med Chem. 2006 Aug 24;49(17):5217-25. doi: 10.1021/jm060469q. J Med Chem. 2006. PMID: 16913710

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