Sheppard DN - Search Results

1

Loop diuretics are open-channel blockers of the cystic fibrosis transmembrane conductance regulator with distinct kinetics.

Ju M, Scott-Ward TS, Liu J, Khuituan P, Li H, Cai Z, Husbands SM, Sheppard DN. Ju M, et al. Among authors: sheppard dn. Br J Pharmacol. 2014 Jan;171(1):265-78. doi: 10.1111/bph.12458. Br J Pharmacol. 2014. PMID: 24117047 Free PMC article.

2

Mechanism of dysfunction of two nucleotide binding domain mutations in cystic fibrosis transmembrane conductance regulator that are associated with pancreatic sufficiency.

Sheppard DN, Ostedgaard LS, Winter MC, Welsh MJ. Sheppard DN, et al. EMBO J. 1995 Mar 1;14(5):876-83. doi: 10.1002/j.1460-2075.1995.tb07069.x. EMBO J. 1995. PMID: 7534226 Free PMC article.

3

Understanding how cystic fibrosis mutations cause a loss of Cl- channel function.

Sheppard DN, Ostedgaard LS. Sheppard DN, et al. Mol Med Today. 1996 Jul;2(7):290-7. doi: 10.1016/1357-4310(96)10028-9. Mol Med Today. 1996. PMID: 8796909 Review.

4

Mechanism of glibenclamide inhibition of cystic fibrosis transmembrane conductance regulator Cl- channels expressed in a murine cell line.

Sheppard DN, Robinson KA. Sheppard DN, et al. J Physiol. 1997 Sep 1;503 ( Pt 2)(Pt 2):333-46. doi: 10.1111/j.1469-7793.1997.333bh.x. J Physiol. 1997. PMID: 9306276 Free PMC article.

5

Comparison of the gating behaviour of human and murine cystic fibrosis transmembrane conductance regulator Cl- channels expressed in mammalian cells.

Lansdell KA, Delaney SJ, Lunn DP, Thomson SA, Sheppard DN, Wainwright BJ. Lansdell KA, et al. Among authors: sheppard dn. J Physiol. 1998 Apr 15;508 ( Pt 2)(Pt 2):379-92. doi: 10.1111/j.1469-7793.1998.379bq.x. J Physiol. 1998. PMID: 9508803 Free PMC article.

6

Regulation of murine cystic fibrosis transmembrane conductance regulator Cl- channels expressed in Chinese hamster ovary cells.

Lansdell KA, Kidd JF, Delaney SJ, Wainwright BJ, Sheppard DN. Lansdell KA, et al. Among authors: sheppard dn. J Physiol. 1998 Nov 1;512 ( Pt 3)(Pt 3):751-64. doi: 10.1111/j.1469-7793.1998.751bd.x. J Physiol. 1998. PMID: 9769419 Free PMC article.

7

Inhibition of heterologously expressed cystic fibrosis transmembrane conductance regulator Cl- channels by non-sulphonylurea hypoglycaemic agents.

Cai Z, Lansdell KA, Sheppard DN. Cai Z, et al. Among authors: sheppard dn. Br J Pharmacol. 1999 Sep;128(1):108-18. doi: 10.1038/sj.bjp.0702748. Br J Pharmacol. 1999. PMID: 10498841 Free PMC article.

8

Two mechanisms of genistein inhibition of cystic fibrosis transmembrane conductance regulator Cl- channels expressed in murine cell line.

Lansdell KA, Cai Z, Kidd JF, Sheppard DN. Lansdell KA, et al. Among authors: sheppard dn. J Physiol. 2000 Apr 15;524 Pt 2(Pt 2):317-30. doi: 10.1111/j.1469-7793.2000.t01-1-00317.x. J Physiol. 2000. PMID: 10766914 Free PMC article.

9

Phloxine B interacts with the cystic fibrosis transmembrane conductance regulator at multiple sites to modulate channel activity.

Cai Z, Sheppard DN. Cai Z, et al. Among authors: sheppard dn. J Biol Chem. 2002 May 31;277(22):19546-53. doi: 10.1074/jbc.M108023200. Epub 2002 Mar 19. J Biol Chem. 2002. PMID: 11904291 Free article.

10

Voltage-dependent gating of the cystic fibrosis transmembrane conductance regulator Cl- channel.

Cai Z, Scott-Ward TS, Sheppard DN. Cai Z, et al. Among authors: sheppard dn. J Gen Physiol. 2003 Nov;122(5):605-20. doi: 10.1085/jgp.200308921. J Gen Physiol. 2003. PMID: 14581585 Free PMC article.

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