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Phase-diagram-guided method for growth of a large crystal of glycoside hydrolase family 45 inverting cellulase suitable for neutron structural analysis.
Nakamura A, Ishida T, Fushinobu S, Kusaka K, Tanaka I, Inaka K, Higuchi Y, Masaki M, Ohta K, Kaneko S, Niimura N, Igarashi K, Samajima M. Nakamura A, et al. Among authors: ohta k. J Synchrotron Radiat. 2013 Nov;20(Pt 6):859-63. doi: 10.1107/S0909049513020943. Epub 2013 Sep 25. J Synchrotron Radiat. 2013. PMID: 24121328 Free PMC article.
Fragment-based discovery of the first nonpeptidyl inhibitor of an S46 family peptidase.
Sakamoto Y, Suzuki Y, Nakamura A, Watanabe Y, Sekiya M, Roppongi S, Kushibiki C, Iizuka I, Tani O, Sakashita H, Inaka K, Tanaka H, Yamada M, Ohta K, Honma N, Shida Y, Ogasawara W, Nakanishi-Matsui M, Nonaka T, Gouda H, Tanaka N. Sakamoto Y, et al. Among authors: ohta k. Sci Rep. 2019 Sep 19;9(1):13587. doi: 10.1038/s41598-019-49984-3. Sci Rep. 2019. PMID: 31537874 Free PMC article.
S46 peptidases are the first exopeptidases to be members of clan PA.
Sakamoto Y, Suzuki Y, Iizuka I, Tateoka C, Roppongi S, Fujimoto M, Inaka K, Tanaka H, Masaki M, Ohta K, Okada H, Nonaka T, Morikawa Y, Nakamura KT, Ogasawara W, Tanaka N. Sakamoto Y, et al. Among authors: ohta k. Sci Rep. 2014 May 15;4:4977. doi: 10.1038/srep04977. Sci Rep. 2014. PMID: 24827749 Free PMC article.
"Newton's cradle" proton relay with amide-imidic acid tautomerization in inverting cellulase visualized by neutron crystallography.
Nakamura A, Ishida T, Kusaka K, Yamada T, Fushinobu S, Tanaka I, Kaneko S, Ohta K, Tanaka H, Inaka K, Higuchi Y, Niimura N, Samejima M, Igarashi K. Nakamura A, et al. Among authors: ohta k. Sci Adv. 2015 Aug 21;1(7):e1500263. doi: 10.1126/sciadv.1500263. eCollection 2015 Aug. Sci Adv. 2015. PMID: 26601228 Free PMC article.
2,952 results