White MA - Search Results

1

Oridonin ring A-based diverse constructions of enone functionality: identification of novel dienone analogues effective for highly aggressive breast cancer by inducing apoptosis.

Ding C, Zhang Y, Chen H, Yang Z, Wild C, Ye N, Ester CD, Xiong A, White MA, Shen Q, Zhou J. Ding C, et al. Among authors: white ma. J Med Chem. 2013 Nov 14;56(21):8814-25. doi: 10.1021/jm401248x. Epub 2013 Oct 31. J Med Chem. 2013. PMID: 24128046 Free PMC article.

2

Efficient Synthesis of ESI-09, A Novel Non-cyclic Nucleotide EPAC Antagonist.

Chen H, Ding C, Wild C, Liu H, Wang T, White MA, Cheng X, Zhou J. Chen H, et al. Among authors: white ma. Tetrahedron Lett. 2013 Mar 20;54(12):1546-1549. doi: 10.1016/j.tetlet.2013.01.024. Tetrahedron Lett. 2013. PMID: 23459418 Free PMC article.

3

Overcoming synthetic challenges of oridonin A-ring structural diversification: regio- and stereoselective installation of azides and 1,2,3-triazoles at the C-1, C-2, or C-3 position.

Ding C, Zhang Y, Chen H, Wild C, Wang T, White MA, Shen Q, Zhou J. Ding C, et al. Among authors: white ma. Org Lett. 2013 Jul 19;15(14):3718-21. doi: 10.1021/ol4015865. Epub 2013 Jul 8. Org Lett. 2013. PMID: 23834026 Free PMC article.

4

ent-Kaurane-based regio- and stereoselective inverse electron demand hetero-Diels-Alder reactions: synthesis of dihydropyran-fused diterpenoids.

Ding C, Wang L, Chen H, Wild C, Ye N, Ding Y, Wang T, White MA, Shen Q, Zhou J. Ding C, et al. Among authors: white ma. Org Biomol Chem. 2014 Nov 14;12(42):8442-52. doi: 10.1039/c4ob01040j. Org Biomol Chem. 2014. PMID: 25225052 Free PMC article.

5

Small-molecule Bax agonists for cancer therapy.

Xin M, Li R, Xie M, Park D, Owonikoko TK, Sica GL, Corsino PE, Zhou J, Ding C, White MA, Magis AT, Ramalingam SS, Curran WJ, Khuri FR, Deng X. Xin M, et al. Among authors: white ma. Nat Commun. 2014 Sep 17;5:4935. doi: 10.1038/ncomms5935. Nat Commun. 2014. PMID: 25230299 Free PMC article.

6

Regio- and Stereospecific Synthesis of Oridonin D-Ring Aziridinated Analogues for the Treatment of Triple-Negative Breast Cancer via Mediated Irreversible Covalent Warheads.

Ding Y, Li D, Ding C, Wang P, Liu Z, Wold EA, Ye N, Chen H, White MA, Shen Q, Zhou J. Ding Y, et al. Among authors: white ma. J Med Chem. 2018 Apr 12;61(7):2737-2752. doi: 10.1021/acs.jmedchem.7b01514. Epub 2018 Mar 20. J Med Chem. 2018. PMID: 29528645 Free PMC article.

7

Design, Synthesis, and Characterization of 4-Undecylpiperidine-2-carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5-HT_2C Receptor.

Wild CT, Miszkiel JM, Wold EA, Soto CA, Ding C, Hartley RM, White MA, Anastasio NC, Cunningham KA, Zhou J. Wild CT, et al. Among authors: white ma. J Med Chem. 2019 Jan 10;62(1):288-305. doi: 10.1021/acs.jmedchem.8b00401. Epub 2018 Apr 13. J Med Chem. 2019. PMID: 29620897 Free PMC article.

8

Design, Synthesis, and Biological Evaluation of Substituted 4,6-Dihydrospiro[[1,2,3]triazolo[4,5-b]pyridine-7,3'-indoline]-2',5(3H)-dione Analogues as Potent NS4B Inhibitors for the Treatment of Dengue Virus Infection.

Xu J, Xie X, Ye N, Zou J, Chen H, White MA, Shi PY, Zhou J. Xu J, et al. Among authors: white ma. J Med Chem. 2019 Sep 12;62(17):7941-7960. doi: 10.1021/acs.jmedchem.9b00698. Epub 2019 Aug 23. J Med Chem. 2019. PMID: 31403780

9

Discovery of phenanthridine analogues as novel chemical probes disrupting the binding of DNA to ΔFosB homodimers and ΔFosB/JunD heterodimers.

Li Y, Liu Z, Aglyamova G, Chen J, Chen H, Bhandari M, White MA, Rudenko G, Zhou J. Li Y, et al. Among authors: white ma. Bioorg Med Chem Lett. 2020 Aug 15;30(16):127300. doi: 10.1016/j.bmcl.2020.127300. Epub 2020 Jun 6. Bioorg Med Chem Lett. 2020. PMID: 32631520 Free PMC article.

10

Mechanism of Epac activation: structural and functional analyses of Epac2 hinge mutants with constitutive and reduced activities.

Tsalkova T, Blumenthal DK, Mei FC, White MA, Cheng X. Tsalkova T, et al. Among authors: white ma. J Biol Chem. 2009 Aug 28;284(35):23644-51. doi: 10.1074/jbc.M109.024950. Epub 2009 Jun 24. J Biol Chem. 2009. PMID: 19553663 Free PMC article.

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