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Inhibition of the cardiomyocyte-specific kinase TNNI3K limits oxidative stress, injury, and adverse remodeling in the ischemic heart.
Vagnozzi RJ, Gatto GJ Jr, Kallander LS, Hoffman NE, Mallilankaraman K, Ballard VL, Lawhorn BG, Stoy P, Philp J, Graves AP, Naito Y, Lepore JJ, Gao E, Madesh M, Force T. Vagnozzi RJ, et al. Among authors: force t. Sci Transl Med. 2013 Oct 16;5(207):207ra141. doi: 10.1126/scitranslmed.3006479. Sci Transl Med. 2013. PMID: 24132636 Free PMC article.
MICU1 motifs define mitochondrial calcium uniporter binding and activity.
Hoffman NE, Chandramoorthy HC, Shamugapriya S, Zhang X, Rajan S, Mallilankaraman K, Gandhirajan RK, Vagnozzi RJ, Ferrer LM, Sreekrishnanilayam K, Natarajaseenivasan K, Vallem S, Force T, Choi ET, Cheung JY, Madesh M. Hoffman NE, et al. Among authors: force t. Cell Rep. 2013 Dec 26;5(6):1576-1588. doi: 10.1016/j.celrep.2013.11.026. Epub 2013 Dec 12. Cell Rep. 2013. PMID: 24332854 Free PMC article.
Sorafenib cardiotoxicity increases mortality after myocardial infarction.
Duran JM, Makarewich CA, Trappanese D, Gross P, Husain S, Dunn J, Lal H, Sharp TE, Starosta T, Vagnozzi RJ, Berretta RM, Barbe M, Yu D, Gao E, Kubo H, Force T, Houser SR. Duran JM, et al. Among authors: force t. Circ Res. 2014 May 23;114(11):1700-1712. doi: 10.1161/CIRCRESAHA.114.303200. Epub 2014 Apr 9. Circ Res. 2014. PMID: 24718482 Free PMC article.
171 results