Xu Y - Search Results

1

Design and Synthesis of Potent Bivalent Peptide Agonists Targeting the EphA2 Receptor.

Duggineni S, Mitra S, Lamberto I, Han X, Xu Y, An J, Pasquale EB, Huang Z. Duggineni S, et al. Among authors: xu y. ACS Med Chem Lett. 2013 Feb 5;4(3):344-8. doi: 10.1021/ml3004523. ACS Med Chem Lett. 2013. PMID: 24167659 Free PMC article.

2

Drug discovery research targeting the CXC chemokine receptor 4 (CXCR4).

Choi WT, Duggineni S, Xu Y, Huang Z, An J. Choi WT, et al. Among authors: xu y. J Med Chem. 2012 Feb 9;55(3):977-94. doi: 10.1021/jm200568c. Epub 2011 Dec 2. J Med Chem. 2012. PMID: 22085380 Free PMC article. Review. No abstract available.

3

Structure-based discovery of a novel inhibitor targeting the β-catenin/Tcf4 interaction.

Tian W, Han X, Yan M, Xu Y, Duggineni S, Lin N, Luo G, Li YM, Han X, Huang Z, An J. Tian W, et al. Among authors: xu y. Biochemistry. 2012 Jan 17;51(2):724-31. doi: 10.1021/bi201428h. Epub 2012 Jan 6. Biochemistry. 2012. PMID: 22224445

4

Design, synthesis and characterization of novel small molecular inhibitors of ephrin-B2 binding to EphB4.

Duggineni S, Mitra S, Noberini R, Han X, Lin N, Xu Y, Tian W, An J, Pasquale EB, Huang Z. Duggineni S, et al. Among authors: xu y. Biochem Pharmacol. 2013 Feb 15;85(4):507-13. doi: 10.1016/j.bcp.2012.12.005. Epub 2012 Dec 17. Biochem Pharmacol. 2013. PMID: 23253822 Free PMC article.

5

A synthetic bivalent ligand of CXCR4 inhibits HIV infection.

Xu Y, Duggineni S, Espitia S, Richman DD, An J, Huang Z. Xu Y, et al. Biochem Biophys Res Commun. 2013 Jun 14;435(4):646-50. doi: 10.1016/j.bbrc.2013.05.038. Epub 2013 May 18. Biochem Biophys Res Commun. 2013. PMID: 23688427 Free PMC article.

6

Discovery and characterization of a novel cyclic peptide that effectively inhibits ephrin binding to the EphA4 receptor and displays anti-angiogenesis activity.

Han X, Xu Y, Yang Y, Xi J, Tian W, Duggineni S, Huang Z, An J. Han X, et al. Among authors: xu y. PLoS One. 2013 Nov 12;8(11):e80183. doi: 10.1371/journal.pone.0080183. eCollection 2013. PLoS One. 2013. PMID: 24265799 Free PMC article.

7

Targeting chemokine receptor CXCR4 for treatment of HIV-1 infection, tumor progression, and metastasis.

Choi WT, Yang Y, Xu Y, An J. Choi WT, et al. Among authors: xu y. Curr Top Med Chem. 2014;14(13):1574-89. doi: 10.2174/1568026614666140827143541. Curr Top Med Chem. 2014. PMID: 25159167 Free PMC article. Review.

8

Development of a novel fluorescence polarization-based assay for studying the β-catenin/Tcf4 interaction.

Tian W, Xu Y, Han X, Duggineni S, Han X, Huang Z, An J. Tian W, et al. Among authors: xu y. J Biomol Screen. 2012 Apr;17(4):530-4. doi: 10.1177/1087057111429745. Epub 2011 Nov 29. J Biomol Screen. 2012. PMID: 22127421

9

Novel Bivalent and D-Peptide Ligands of CXCR4 Mobilize Hematopoietic Progenitor Cells to the Blood in C3H/HeJ Mice.

Mao Y, Meng Q, Song P, Zhu S, Xu Y, Snyder EY, An J, Huang Z. Mao Y, et al. Among authors: xu y. Cell Transplant. 2018 Aug;27(8):1249-1255. doi: 10.1177/0963689718784957. Epub 2018 Jul 11. Cell Transplant. 2018. PMID: 29991278 Free PMC article.

10

Critical role in CXCR4 signaling and internalization of the polypeptide main chain in the amino terminus of SDF-1α probed by novel N-methylated synthetically and modularly modified chemokine analogues.

Dong CZ, Tian S, Choi WT, Kumar S, Liu D, Xu Y, Han X, Huang Z, An J. Dong CZ, et al. Among authors: xu y. Biochemistry. 2012 Jul 31;51(30):5951-7. doi: 10.1021/bi3003742. Epub 2012 Jul 23. Biochemistry. 2012. PMID: 22779681 Free PMC article.

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